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Advances in osteoclast biology reveal potential new drug targets and new roles for osteoclasts

Journal of bone and mineral research, 2013-04, Vol.28 (4), p.711-722

Boyce, Brendan F

2013

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Functions of RANKL/RANK/OPG in bone modeling and remodeling

Archives of biochemistry and biophysics, 2008-05, Vol.473 (2), p.139-146

2008

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Biology of RANK, RANKL, and osteoprotegerin

Arthritis research & therapy, 2007-01, Vol.9 Suppl 1 (Suppl 1), p.S1-S1

2007

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Age-associated callus senescent cells produce TGF-β1 that inhibits fracture healing in aged mice

The Journal of clinical investigation, 2022-04, Vol.132 (8), p.1-17

2022

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B cells inhibit bone formation in rheumatoid arthritis by suppressing osteoblast differentiation

Nature communications, 2018-12, Vol.9 (1), p.5127-14, Article 5127

2018

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NF-κB-Mediated Regulation of Osteoclastogenesis

Endocrinology and Metabolism, 2015, 30(1), , pp.35-44

2015

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High-Fat Diet Causes Bone Loss in Young Mice by Promoting Osteoclastogenesis Through Alteration of the Bone Marrow Environment

Calcified tissue international, 2015-04, Vol.96 (4), p.313-323

2015

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TGFβ-induced degradation of TRAF3 in mesenchymal progenitor cells causes age-related osteoporosis

Nature communications, 2019-06, Vol.10 (1), p.2795-15, Article 2795

2019

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Bone Remodeling and the Role of TRAF3 in Osteoclastic Bone Resorption

Frontiers in immunology, 2018-09, Vol.9, p.2263-2263

2018

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Targeting Notch‐Activated M1 Macrophages Attenuates Joint Tissue Damage in a Mouse Model of Inflammatory Arthritis

Journal of bone and mineral research, 2017-07, Vol.32 (7), p.1469-1480

2017

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Proteasome inhibition-enhanced fracture repair is associated with increased mesenchymal progenitor cells in mice

PloS one, 2022-02, Vol.17 (2), p.e0263839-e0263839

2022

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Evolving concepts in bone infection: redefining "biofilm", "acute vs. chronic osteomyelitis", "the immune proteome" and "local antibiotic therapy"

Bone Research, 2019-07, Vol.7 (1), p.20-18, Article 20

2019

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Dimorphic effects of Notch signaling in bone homeostasis

Nature medicine, 2008-03, Vol.14 (3), p.299-305

2008

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TNF Induction of NF-κB RelB Enhances RANKL-Induced Osteoclastogenesis by Promoting Inflammatory Macrophage Differentiation but also Limits It through Suppression of NFATc1 Expression

PloS one, 2015-08, Vol.10 (8), p.e0135728-e0135728

2015

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Molecular signatures distinguish senescent cells from inflammatory cells in aged mouse callus stromal cells

Frontiers in endocrinology (Lausanne), 2023-02, Vol.14, p.1090049-1090049

2023

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TGFβ1 + CCR5 + neutrophil subset increases in bone marrow and causes age-related osteoporosis in male mice

Nature communications, 2023-01, Vol.14 (1), p.159-159, Article 159

2023

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Nuclear Factor-Kappa B Regulation of Osteoclastogenesis and Osteoblastogenesis

Endocrinology and Metabolism, 2023, 38(5), , pp.504-521

2023

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HSF1 is a driver of leukemia stem cell self-renewal in acute myeloid leukemia

Nature communications, 2022-10, Vol.13 (1), p.6107-6107, Article 6107

2022

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Vascular endothelial growth factor C attenuates joint damage in chronic inflammatory arthritis by accelerating local lymphatic drainage in mice

Arthritis & rheumatology (Hoboken, N.J.), 2011-08, Vol.63 (8), p.2318-2328

2011

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Lymphatic endothelial cells efferent to inflamed joints produce iNOS and inhibit lymphatic vessel contraction and drainage in TNF-induced arthritis in mice

Arthritis research & therapy, 2016-03, Vol.18 (62), p.62-62, Article 62

2016

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Increased bone density in mice lacking the proton receptor OGR1

Kidney international, 2016-03, Vol.89 (3), p.565-573

2016

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Osteoclast precursors, RANKL/RANK, and immunology

Immunological reviews, 2005-12, Vol.208 (1), p.19-29

2005

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Tumor Necrosis Factor Promotes Runx2 Degradation through Up-regulation of Smurf1 and Smurf2 in Osteoblasts

The Journal of biological chemistry, 2006-02, Vol.281 (7), p.4326-4333

2006

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RelB/p50 complexes regulate cytokine-induced YKL-40 expression

The Journal of immunology (1950), 2015-03, Vol.194 (6), p.2862-2870

2015

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Avian Reticuloendotheliosis Viral Oncogene Related B Regulates Lymphatic Endothelial Cells during Vessel Maturation and Is Required for Lymphatic Vessel Function in Adult Mice

The American journal of pathology, 2019-12, Vol.189 (12), p.2516-2530

2019

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Advances in osteoclast biology reveal potential new drug targets and new roles for osteoclasts

Functions of RANKL/RANK/OPG in bone modeling and remodeling

Biology of RANK, RANKL, and osteoprotegerin

Age-associated callus senescent cells produce TGF-β1 that inhibits fracture healing in aged mice

B cells inhibit bone formation in rheumatoid arthritis by suppressing osteoblast differentiation

NF-κB-Mediated Regulation of Osteoclastogenesis

High-Fat Diet Causes Bone Loss in Young Mice by Promoting Osteoclastogenesis Through Alteration of the Bone Marrow Environment

TGFβ-induced degradation of TRAF3 in mesenchymal progenitor cells causes age-related osteoporosis

Bone Remodeling and the Role of TRAF3 in Osteoclastic Bone Resorption

Targeting Notch‐Activated M1 Macrophages Attenuates Joint Tissue Damage in a Mouse Model of Inflammatory Arthritis

Proteasome inhibition-enhanced fracture repair is associated with increased mesenchymal progenitor cells in mice

Evolving concepts in bone infection: redefining "biofilm", "acute vs. chronic osteomyelitis", "the immune proteome" and "local antibiotic therapy"

Dimorphic effects of Notch signaling in bone homeostasis

TNF Induction of NF-κB RelB Enhances RANKL-Induced Osteoclastogenesis by Promoting Inflammatory Macrophage Differentiation but also Limits It through Suppression of NFATc1 Expression

Molecular signatures distinguish senescent cells from inflammatory cells in aged mouse callus stromal cells

TGFβ1 + CCR5 + neutrophil subset increases in bone marrow and causes age-related osteoporosis in male mice

Nuclear Factor-Kappa B Regulation of Osteoclastogenesis and Osteoblastogenesis

HSF1 is a driver of leukemia stem cell self-renewal in acute myeloid leukemia

Vascular endothelial growth factor C attenuates joint damage in chronic inflammatory arthritis by accelerating local lymphatic drainage in mice

Lymphatic endothelial cells efferent to inflamed joints produce iNOS and inhibit lymphatic vessel contraction and drainage in TNF-induced arthritis in mice

Increased bone density in mice lacking the proton receptor OGR1

Osteoclast precursors, RANKL/RANK, and immunology

Tumor Necrosis Factor Promotes Runx2 Degradation through Up-regulation of Smurf1 and Smurf2 in Osteoblasts

RelB/p50 complexes regulate cytokine-induced YKL-40 expression

Avian Reticuloendotheliosis Viral Oncogene Related B Regulates Lymphatic Endothelial Cells during Vessel Maturation and Is Required for Lymphatic Vessel Function in Adult Mice

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