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Soybean phenolic-rich extracts inhibit key-enzymes linked to type 2 diabetes (α-amylase and α-glucosidase) and hypertension (angiotensin I converting enzyme) in vitro

Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie, 2013-03, Vol.65 (3), p.305-309

2013

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In vitro studies of eggplant ( Solanum melongena) phenolics as inhibitors of key enzymes relevant for type 2 diabetes and hypertension

Bioresource technology, 2008-05, Vol.99 (8), p.2981-2988

2008

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Kinetics and Molecular Docking Studies of the Inhibitions of Angiotensin Converting Enzyme and Renin Activities by Hemp Seed (Cannabis sativa L.) Peptides

Journal of agricultural and food chemistry, 2014-05, Vol.62 (18), p.4135-4144

2014

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Investigation on the metabolic characteristics of isobavachin in Psoralea corylifolia L. (Bu‐gu‐zhi) and its potential inhibition against human cytochrome P450s and UDP‐glucuronosyltransferases

Journal of pharmacy and pharmacology, 2020-12, Vol.72 (12), p.1865-1878

2020

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Two novel peptides with angiotensin I converting enzyme inhibitory and antioxidative activities from Scorpaena notata muscle protein hydrolysate

Biotechnology and applied biochemistry, 2017-03, Vol.64 (2), p.201-210

2017

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Phenolic profiles of 20 Canadian lentil cultivars and their contribution to antioxidant activity and inhibitory effects on α-glucosidase and pancreatic lipase

Food chemistry, 2015-04, Vol.172, p.862-872

2015

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Favipiravir (T-705), a novel viral RNA polymerase inhibitor

Antiviral research, 2013-11, Vol.100 (2), p.446-454

2013

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Bioactive peptides from Atlantic salmon (Salmo salar) with angiotensin converting enzyme and dipeptidyl peptidase IV inhibitory, and antioxidant activities

Food chemistry, 2017-03, Vol.218, p.396-405

2017

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Inhibitory activities of Cystoseira crinita sulfated polysaccharide on key enzymes related to diabetes and hypertension: in vitro and animal study

Archives of physiology and biochemistry, 2017-02, Vol.123 (1), p.31-42

2017

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Extraction and characterization of phycocyanin from Spirulina platensis and evaluation of its anticancer, antidiabetic and antiinflammatory effect

International journal of biological macromolecules, 2020-06, Vol.153, p.256-263

2020

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Bound Phenolics of Quinoa Seeds Released by Acid, Alkaline, and Enzymatic Treatments and Their Antioxidant and α‑Glucosidase and Pancreatic Lipase Inhibitory Effects

Journal of agricultural and food chemistry, 2016-03, Vol.64 (8), p.1712-1719

2016

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Scrophularia lucida L. as a valuable source of bioactive compounds for pharmaceutical applications: In vitro antioxidant, anti-inflammatory, enzyme inhibitory properties, in silico studies, and HPLC profiles

Journal of pharmaceutical and biomedical analysis, 2019-01, Vol.162, p.225-233

2019

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Recent advances in biosensors based on enzyme inhibition

Biosensors & bioelectronics, 2016-02, Vol.76, p.180-194

2016

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Characterization, antioxidant activity, and inhibitory effect on pancreatic lipase of extracts from the edible insects Acheta domesticus and Tenebrio molitor

Food chemistry, 2020-03, Vol.309, p.125742-125742, Article 125742

2020

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A cell-based screen identifies ATR inhibitors with synthetic lethal properties for cancer-associated mutations

Nature structural & molecular biology, 2011-06, Vol.18 (6), p.721-727

2011

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Discovery of Soluble Epoxide Hydrolase Inhibitors from Chemical Synthesis and Natural Products

Journal of medicinal chemistry, 2021-01, Vol.64 (1), p.184-215

2021

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Rapid screening and identification of α-glucosidase inhibitors from mulberry leaves using enzyme-immobilized magnetic beads coupled with HPLC/MS and NMR

Biomedical chromatography, 2013-02, Vol.27 (2), p.148-155

2013

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Scorpion venom components as potential candidates for drug development

Toxicon (Oxford), 2015-01, Vol.93, p.125-135

2015

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Production of ACE inhibitory peptides from sweet sorghum grain protein using alcalase: Hydrolysis kinetic, purification and molecular docking study

Food chemistry, 2016-05, Vol.199, p.140-149

2016

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In Vitro and in Vivo Studies on the Angiotensin-Converting Enzyme Inhibitory Activity Peptides Isolated from Broccoli Protein Hydrolysate

Journal of agricultural and food chemistry, 2019-06, Vol.67 (24), p.6757-6764

2019

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Exploring the potential of novel xanthine oxidase inhibitory peptide (ACECD) derived from Skipjack tuna hydrolysates using affinity-ultrafiltration coupled with HPLC–MALDI-TOF/TOF-MS

Food chemistry, 2021-06, Vol.347, p.129068-129068, Article 129068

2021

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Nine novel angiotensin I-converting enzyme (ACE) inhibitory peptides from cuttlefish (Sepia officinalis) muscle protein hydrolysates and antihypertensive effect of the potent active peptide in spontaneously hypertensive rats

Food chemistry, 2015-03, Vol.170, p.519-525

2015

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Exploring Marine-Derived Ascochlorins as Novel Human Dihydroorotate Dehydrogenase Inhibitors for Treatment of Triple-Negative Breast Cancer

Journal of medicinal chemistry, 2021-09, Vol.64 (18), p.13918-13932

2021

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Identification and characterization of new potent inhibitors of dengue virus NS5 proteinase from Andrographis paniculata supercritical extracts on in animal cell culture and in silico approaches

Journal of ethnopharmacology, 2021-03, Vol.267, p.113541, Article 113541

2021

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Soybean phenolic-rich extracts inhibit key-enzymes linked to type 2 diabetes (α-amylase and α-glucosidase) and hypertension (angiotensin I converting enzyme) in vitro

In vitro studies of eggplant ( Solanum melongena) phenolics as inhibitors of key enzymes relevant for type 2 diabetes and hypertension

Kinetics and Molecular Docking Studies of the Inhibitions of Angiotensin Converting Enzyme and Renin Activities by Hemp Seed (Cannabis sativa L.) Peptides

Investigation on the metabolic characteristics of isobavachin in Psoralea corylifolia L. (Bu‐gu‐zhi) and its potential inhibition against human cytochrome P450s and UDP‐glucuronosyltransferases

Two novel peptides with angiotensin I converting enzyme inhibitory and antioxidative activities from Scorpaena notata muscle protein hydrolysate

Phenolic profiles of 20 Canadian lentil cultivars and their contribution to antioxidant activity and inhibitory effects on α-glucosidase and pancreatic lipase

Favipiravir (T-705), a novel viral RNA polymerase inhibitor

Bioactive peptides from Atlantic salmon (Salmo salar) with angiotensin converting enzyme and dipeptidyl peptidase IV inhibitory, and antioxidant activities

Inhibitory activities of Cystoseira crinita sulfated polysaccharide on key enzymes related to diabetes and hypertension: in vitro and animal study

Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia

Extraction and characterization of phycocyanin from Spirulina platensis and evaluation of its anticancer, antidiabetic and antiinflammatory effect

Bound Phenolics of Quinoa Seeds Released by Acid, Alkaline, and Enzymatic Treatments and Their Antioxidant and α‑Glucosidase and Pancreatic Lipase Inhibitory Effects

Scrophularia lucida L. as a valuable source of bioactive compounds for pharmaceutical applications: In vitro antioxidant, anti-inflammatory, enzyme inhibitory properties, in silico studies, and HPLC profiles

Recent advances in biosensors based on enzyme inhibition

Characterization, antioxidant activity, and inhibitory effect on pancreatic lipase of extracts from the edible insects Acheta domesticus and Tenebrio molitor

A cell-based screen identifies ATR inhibitors with synthetic lethal properties for cancer-associated mutations

Discovery of Soluble Epoxide Hydrolase Inhibitors from Chemical Synthesis and Natural Products

Rapid screening and identification of α-glucosidase inhibitors from mulberry leaves using enzyme-immobilized magnetic beads coupled with HPLC/MS and NMR

Scorpion venom components as potential candidates for drug development

Production of ACE inhibitory peptides from sweet sorghum grain protein using alcalase: Hydrolysis kinetic, purification and molecular docking study

In Vitro and in Vivo Studies on the Angiotensin-Converting Enzyme Inhibitory Activity Peptides Isolated from Broccoli Protein Hydrolysate

Exploring the potential of novel xanthine oxidase inhibitory peptide (ACECD) derived from Skipjack tuna hydrolysates using affinity-ultrafiltration coupled with HPLC–MALDI-TOF/TOF-MS

Nine novel angiotensin I-converting enzyme (ACE) inhibitory peptides from cuttlefish (Sepia officinalis) muscle protein hydrolysates and antihypertensive effect of the potent active peptide in spontaneously hypertensive rats

Exploring Marine-Derived Ascochlorins as Novel Human Dihydroorotate Dehydrogenase Inhibitors for Treatment of Triple-Negative Breast Cancer

Identification and characterization of new potent inhibitors of dengue virus NS5 proteinase from Andrographis paniculata supercritical extracts on in animal cell culture and in silico approaches

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