Journal of the neurological sciences, 2012-02, Vol.313 (1), p.54-56
2012
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- Autor(en) / Beteiligte
- Titel
- Widespread cerebral cortical mineralization in Wilson's disease detected by susceptibility-weighted imaging
- Ist Teil von
- Journal of the neurological sciences, 2012-02, Vol.313 (1), p.54-56
- Ort / Verlag
- Amsterdam: Elsevier B.V
- Erscheinungsjahr
- 2012
- Quelle
- ScienceDirect
- Beschreibungen/Notizen
- Abstract Signal abnormalities of cortical gray matter, compared with the deep nuclear structures, have received less attention in Wilson's disease (WD). They nearly always accompanied white matter signal change, and commonly are associated with epilepsy and psychiatric features. We report herein two cases diagnosed as WD who, in addition to characteristic deep nuclear lesions on MR imaging, had widespread cerebral cortical paramagnetic signals dramatically detected by susceptibility-weighted imaging. T2-weighted MR images did not show any cortico-subcortical hyperintense lesions. To our knowledge, these findings have not been described before and may help to further characterize the disease.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0022-510XeISSN: 1878-5883DOI: 10.1016/j.jns.2011.09.031Titel-ID: cdi_proquest_miscellaneous_923209237
- Format
- –
- Schlagworte
- Adult, Biological and medical sciences, Calcinosis - diagnosis, Calcinosis - metabolism, Calcinosis - pathology, Cerebral Cortex - metabolism, Cerebral Cortex - pathology, Cortex, Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases, Diffusion Magnetic Resonance Imaging - methods, Disease Susceptibility - metabolism, Disease Susceptibility - pathology, Hepatolenticular Degeneration - diagnosis, Hepatolenticular Degeneration - metabolism, Hepatolenticular Degeneration - pathology, Humans, Male, Medical sciences, Neurology, Susceptibility-weighted imaging, Wilson's disease