Sie befinden Sich nicht im Netzwerk der Universität Paderborn. Der Zugriff auf elektronische Ressourcen ist gegebenenfalls nur via VPN oder Shibboleth (DFN-AAI) möglich. mehr Informationen...
•Supramolecular interactions between MOFs and biomolecules are reviewed.•Evidence from crystallography, spectroscopy and computational methods is assessed.•Intraframework interactions have an impact on the availability of functional groups so are discussed too.•Case studies showing how the techniques work together are also highlighted.
This review focusses on the supramolecular interactions between metal–organic frameworks (MOFs) and included biomolecules. Examples demonstrating the utility of crystallography, spectroscopic techniques, and computational modelling for probing such interactions are highlighted. Key papers illustrating the importance of intraframework interactions to the structure, flexibility, and availability of functional groups in bioMOFs are also discussed. Finally, a range of case studies focussing on applications relating to biosensing, drug delivery, contaminant removal and enzyme immobilisation are discussed as a means of highlighting how the various characterisation techniques can work together to provide an enhanced understanding of the supramolecular chemistry involved and their effects on the application.