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Glycemic status, lipid profile and proteinuria in diabetic nephropathy
Ist Teil von
Journal of Nepal Medical Association, 2010-04, Vol.49 (178), p.143-146
Ort / Verlag
Nepal: Nepal Medical Association
Erscheinungsjahr
2010
Link zum Volltext
Quelle
EZB Free E-Journals
Beschreibungen/Notizen
Diabetic nephropathy is one of the major complications of Diabetes Mellitus characterized by persistent albuminuria, elevated arterial blood pressure, a relentless decline in glomerular filtration rate (GFR) and a high risk of cardiovascular morbidity and mortality.
In this study, urinary micro-albumin estimation was done in 177 diabetic patients. This study aims to ascertain association of glycemic status, lipid profile and proteinuria in Type 2 Diabetes Mellitus with nephropathy.
Among 177 patients, 26 had frank proteinuria, 79 had micro-albuminuria and 72 were without proteinuria. Increased frequency of proteinuria was seen in male than female. Micro-albuminuria and frank proteinuria was seen more in older age group. The multiple comparisons showed the significantly increased levels of urea, creatinine, fasting blood glucose in micro-albuminuria and overt proteinuria patients in comparison to without proteinuria. Glycated hemoglobin level was increased with the increasing age group particularly in overt proteinuric patients.
The glycemic control, monitoring of lipid profile and early urinary protein estimation with better management may delay diabetic nephropathy or its further complications in diabetes mellitus.