Details

Autor(en) / Beteiligte

• Farjami, Afsaneh
• Jouyban, Abolghasem

Titel

Solubility of Tadalafil in Pharmaceutical Solvent Mixtures at 298.2K

Ist Teil von

• Chemical engineering communications, 2015-11, Vol.202 (11), p.1522-1527

Ort / Verlag

Philadelphia: Taylor & Francis

Erscheinungsjahr

2015

Quelle

Taylor & Francis

Beschreibungen/Notizen

• The experimental solubility of tadalafil in binary mixtures of ethanol (EtOH) + water, propylene glycol (PG) + water, polyethylene glycol 200 (PEG 200) + water, polyethylene glycol 400 (PEG 400) + water, and ternary mixtures of PEG 200 + PG + EtOH at 298.2 K were assessed. The experimental data were fitted to the Jouyban-Acree model. The mean percent deviations (MPD) of the back-calculated solubilities for EtOH + water, PG +water, PEG 200 + water, PEG 400 + water, and PEG 200 + PG + EtOH mixtures were 7.4%, 11.3%, 14.0%, 18.5%, and 5.6%, respectively and the overall MPD was 11.0%.