Details

Autor(en) / Beteiligte

• Xia, Minfang
• Hu, Weiming
• Sun, Song
• Yu, Jin-Tao
• Cheng, Jiang

Titel

The dearomative annulation between N-2-pyridylamidine and CO2 toward pyrido[1,2-a]-1,3,5-triazin-4-onesElectronic supplementary information (ESI) available. See DOI: 10.1039/c7ob00777a

Erscheinungsjahr

2017-05

Link zum Volltext

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• A base-promoted dearomative annulation between N -2-pyridylamidine and an atmospheric pressure of CO 2 was developed, affording a series of pyrido[1,2- a ]-1,3,5-triazin-4-ones in moderate to excellent yields. CO 2 served as a carbonyl source, releasing H 2 O as a solely clean byproduct. Moreover, no dehydrating reagent and transition-metal catalyst were required in this procedure. Thus, it represents a green, sustainable and straightforward pathway to access such frameworks. A base-promoted dearomative annulation between N -2-pyridylamidine and an atmospheric pressure of CO 2 was developed, affording a series of pyrido[1,2- a ]-1,3,5-triazin-4-ones in moderate to excellent yields.