Internal Medicine, 2020/12/15, Vol.59(24), pp.3187-3193
2020
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- Autor(en) / Beteiligte
- Titel
- Ectopic Relapse of Anti-neutrophil Cytoplasmic Antibody-associated Pituitary Vasculitis with No Elevation of Anti-neutrophil Cytoplasmic Antibodies after Renal Remission
- Ist Teil von
- Internal Medicine, 2020/12/15, Vol.59(24), pp.3187-3193
- Ort / Verlag
- Japan: The Japanese Society of Internal Medicine
- Erscheinungsjahr
- 2020
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- The relationship between anti-neutrophil cytoplasmic antibody (ANCA) titer levels and relapse risk in patients with ANCA-associated vasculitis (AAV) following clinical remission remains controversial. We herein report a case showing ectopic relapse of AAV in the pituitary with no ANCA elevation after renal remission. Magnetic resonance imaging revealed an enlarged pituitary gland. A pituitary biopsy showed geographic necrosis with multinucleated giant cells. We diagnosed this case as relapse of AAV in the pituitary. One month after rituximab therapy, the pituitary gland volume had decreased. The intensification of therapy due to the possibility of vasculitis relapse may facilitate better control of AAV.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0918-2918eISSN: 1349-7235DOI: 10.2169/internalmedicine.4731-20Titel-ID: cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7807102
- Format
- –
- Schlagworte
- ANCA, ANCA-associated vasculitis, Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis - diagnosis, Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis - drug therapy, Antibodies, Antineutrophil Cytoplasmic, Antineutrophil cytoplasmic antibodies, Biopsy, Case Report, Case reports, Giant cells, Humans, Internal medicine, Kidney, Magnetic resonance imaging, Monoclonal antibodies, Neutrophils, Pituitary, Pituitary Gland, Recurrence, relapse, Remission, Remission Induction, Rituximab, Rituximab - therapeutic use, Vasculitis