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A 66-year-old man with hypertension, diabetes, hyperlipidemia, obesity, chronic kidney disease, and end-stage liver disease, for which he had undergone liver transplantation, presented with fever, cough, dyspnea, and hypoxemia during the Covid-19 pandemic. Chest radiography revealed patchy confluent airspace opacities in the mid-to-lower lungs. Management decisions were made.