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Minimally Invasive Microbiopsies as an Improved Sampling Method for the Diagnosis of Cutaneous Leishmaniasis
Ist Teil von
Open forum infectious diseases, 2020-09, Vol.7 (9), p.ofaa364-ofaa364
Ort / Verlag
US: Oxford University Press
Erscheinungsjahr
2020
Link zum Volltext
Quelle
EZB Free E-Journals
Beschreibungen/Notizen
Abstract
Current sampling methods to diagnose cutaneous leishmaniasis are invasive and painful. An alternative and minimally invasive microbiopsy device was evaluated in a diverse range of cutaneous leishmaniasis lesions in Ethiopia. Using polymerase chain reaction–based diagnosis, the microbiopsy outperformed the routine skin slit sample by detecting more patients while pain scores were significantly lower.
Current sampling methods to diagnose cutaneous leishmaniasis are invasive and painful. In diverse lesion types and using PCR-based diagnosis, a novel and minimally-invasive microbiopsy outperformed the routine skin slit sample by detecting more patients while pain scores were significantly lower.