Details

Autor(en) / Beteiligte

• Hatayama, Mayumi
• Ikuta, Katsuya
• Ishioh, Masatomo
• Saito, Takeshi
• Toki, Yasumichi
• Yamamoto, Masayo
• Shindo, Motohiro
• Torimoto, Yoshihiro
• Okumura, Toshikatsu

Titel

Pseudogout Attack after Pegfilgrastim Administration in Anaplastic Large Cell Lymphoma

Ist Teil von

• Internal Medicine, 2018/06/15, Vol.57(12), pp.1779-1782

Ort / Verlag

Japan: The Japanese Society of Internal Medicine

Erscheinungsjahr

2018

Quelle

MEDLINE

Beschreibungen/Notizen

• A 67-year-old man with relapsed anaplastic large cell lymphoma received salvage chemotherapy, and pegfilgrastim was used to prevent febrile neutropenia. On day 18 of chemotherapy, he developed a pseudogout attack. Although the first symptoms improved, another pseudogout attack occurred when he received the second course of chemotherapy and pegfilgrastim. Filgrastim was then used for the third course of chemotherapy, and a pseudogout attack did not occur. The serum granulocyte-stimulating factor (G-CSF) level was extremely elevated only when pegfilgrastim was used, suggesting a relationship between pseudogout and G-CSF. Pseudogout should be recognized as an adverse effect of pegfilgrastim.