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  • BibTeX
Pneumocystis Pneumonia Concomitant with Ectopic ACTH Syndrome Caused by a Large Cell Neuroendocrine Carcinoma of the Thymus
Internal Medicine, 2017/03/01, Vol.56(5), pp.551-555
2017

Details

Autor(en) / Beteiligte
Titel
Pneumocystis Pneumonia Concomitant with Ectopic ACTH Syndrome Caused by a Large Cell Neuroendocrine Carcinoma of the Thymus
Ist Teil von
  • Internal Medicine, 2017/03/01, Vol.56(5), pp.551-555
Ort / Verlag
Japan: The Japanese Society of Internal Medicine
Erscheinungsjahr
2017
Link zum Volltext
Quelle
EZB-FREE-00999 freely available EZB journals
Beschreibungen/Notizen
  • We herein report the case of a 44-year-old man who was diagnosed with pneumocystis pneumonia (PCP) concomitant with ectopic adrenocorticotropic hormone (ACTH) syndrome, which had been caused by a large cell neuroendocrine carcinoma of the thymus. Chest computed tomography revealed ground-glass opacities in the lungs. PCP was diagnosed by a polymerase chain reaction with bronchoalveolar lavage. The levels of cortisol were slowly corrected with an adrenal enzyme inhibitor, and the exacerbation of PCP was successfully avoided. Our case indicates that in addition to prophylaxis, the early diagnosis of PCP and the slow correction of hypercortisolemia should be considered in order to prevent an exacerbation due to the reconstitution of the immune function in patients with ectopic ACTH syndrome.
Sprache
Englisch
Identifikatoren
ISSN: 0918-2918
eISSN: 1349-7235
DOI: 10.2169/internalmedicine.56.7655
Titel-ID: cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5399209
Format
–
Schlagworte
ACTH Syndrome, Ectopic - complications, ACTH Syndrome, Ectopic - drug therapy, Adrenal glands, Adrenocorticotropic hormone, Adult, Alveoli, Bronchoalveolar Lavage, Bronchus, Carcinoma, Neuroendocrine - complications, Case Report, Computed tomography, Cortisol, Cushing's syndrome, Early Diagnosis, ectopic ACTH syndrome, Enzyme inhibitors, Enzyme Inhibitors - therapeutic use, Humans, Hydrocortisone - blood, Immune response, Internal medicine, large cell neuroendocrine carcinoma, Male, Metyrapone - therapeutic use, neuroendocrine tumor, Neuroendocrine tumors, Opportunistic Infections - complications, Opportunistic Infections - diagnosis, Pneumocystis, pneumocystis pneumonia, Pneumonia, Pneumonia, Pneumocystis - complications, Pneumonia, Pneumocystis - diagnosis, Polymerase chain reaction, Prophylaxis, Thymus, Thymus Neoplasms - complications, Tomography, X-Ray Computed

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