Details

Autor(en) / Beteiligte

• Jansson, Moritz
• Beissner, Marcus
• Phillips, Richard Odame
• Badziklou, Kossi
• Piten, Ebekalisai
• Maman, Issaka
• Sarfo, Fred Stephen
• Huber, Kristina Lydia
• Rhomberg, Agata
• Symank, Dominik
• Wagner, Magdalena
• Wiedemann, Franz
• Nitschke, Jörg
• Banla Kere, Abiba
• Herbinger, Karl-Heinz
• Adjei, Ohene
• Löscher, Thomas
• Bretzel, Gisela
• Land, G. A.

Titel

Comparison of two assays for molecular determination of rifampin resistance in clinical samples from patients with Buruli ulcer disease

Ist Teil von

• Journal of clinical microbiology, 2014-04, Vol.52 (4), p.1246-1249

Ort / Verlag

United States: American Society for Microbiology

Erscheinungsjahr

2014

Link zum Volltext

Quelle

EZB Free E-Journals

Beschreibungen/Notizen

• This study evaluates a novel assay for detecting rifampin resistance in clinical Mycobacterium ulcerans isolates. Although highly susceptible for PCR inhibitors in 50% of the samples tested, the assay was 100% M. ulcerans specific and yielded >98% analyzable sequences with a lower limit of detection of 100 to 200 copies of the target sequence.