Sie befinden Sich nicht im Netzwerk der Universität Paderborn. Der Zugriff auf elektronische Ressourcen ist gegebenenfalls nur via VPN oder Shibboleth (DFN-AAI) möglich. mehr Informationen...
Beckwith-Wiedemann syndrome and assisted reproduction technology (ART)
Ist Teil von
Journal of medical genetics, 2003-01, Vol.40 (1), p.62-64
Ort / Verlag
England: BMJ Publishing Group Ltd
Erscheinungsjahr
2003
Quelle
MEDLINE
Beschreibungen/Notizen
To test the significance of the observed and expected frequencies we used a Poisson approximation to the binomial distribution and obtained a two tailed p value of 0.018. [...]the observed frequency (n=6) of IVF and ICSI births in the BWS series is significantly greater than the expected (1.7252), with an associated 95% confidence interval on the excess risk of 1.5, 8.8. Had such data been available, then this would have very probably reduced the expected number of BWS births after IVF or ICSI, as the birth rate in the general population has been declining since 1989 and the annual number of ART births before 1995 would have been less than during the five years included in the comparison. [...]our comparison is likely to be conservative in relation to calendar year.