Autor(en)
Krogsaeter, Einar; Tang, Rachel; Grimm, Christian
Titel
JPT2: The missing link between intracellular Ca 2+ release channels and NAADP?
Teil von
  • Cell calcium (Edinburgh), 2021-04-14, Vol.97, p.102405
Ort / Verlag
Netherlands
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Beschreibungen
NAADP (nicotinic acid adenine dinucleotide phosphate) is a potent second messenger releasing Ca from endolysosomes through two-pore channels (TPCs) and from the endoplasmic reticulum (ER) through type 1 ryanodine receptors (RyR1). How NAADP activates these channels, whether directly or indirectly, has been a matter of debate for more than a decade. Now a protein has emerged possibly providing the missing link between TPCs/RyR1 and NAADP.
Format
Sprache(n)
Englisch
Identifikator(en)
ISSN: 1532-1991
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