Details

Autor(en) / Beteiligte

• Guan, Xiaosheng
• Zhao, Zhijun
• Cai, Siyi
• Wang, Shuxiao
• Lu, Hua

Titel

Analysis of volatile organic compounds using cryogen-free thermal modulation based comprehensive two-dimensional gas chromatography coupled with quadrupole mass spectrometry

Ist Teil von

• Journal of Chromatography A, 2019-02, Vol.1587, p.227-238

Ort / Verlag

Elsevier B.V

Erscheinungsjahr

2019

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• •A novel single-channel GCxGC-qMS system using a solid-state modulator successfully separates target atmospheric VOCs from C2 to C12 without any cryogen use and channel switching activity.•A hybrid primary column composed of a PLOT part and a general mid-polar column exhibits improved separation performance for C2-C4 compounds in the first dimension.•Target and non-target analysis of real atmospheric samples from coal combustion and ambient air from an indutrial area are accomplished using this low-resource GCxGC-qMS system. A single-channel comprehensive two-dimensional gas chromatography-quadrupole mass spectrometry (GCxGC-qMS) system was developed using a recently introduced solid-state thermal modulator. By modulation on a special column, extremely light hydrocarbons down to C2 can be successfully modulated without use of any cryogens. Paired with a polar secondary dimension column, a hybrid primary dimension column was developed to provide complete two-dimensional separation of all target volatile organic compounds (VOCs) from C2 to C12. This single-channel GCxGC-qMS system is used to analyze VOC standards containing 57 PAMS and 64 TO-15 gas mixtures, as well as real-world samples. This study demonstrates that a low resource GCxGC-qMS system may serve as a feasible tool for routine VOCs monitoring.