Details

Autor(en) / Beteiligte

• Mikhaĭlov, A I
• Panov, V O
• Tiurin, I E

Titel

Whole-body diffusion-weighted magnetic resonance imaging by estimating the measurable diffusion coefficient in Hodgkin Iymphoma

Ist Teil von

• Vestnik rentgenologii i radiologii, 2015-03 (2), p.28

Ort / Verlag

Russia (Federation)

Erscheinungsjahr

2015

Link zum Volltext

Beschreibungen/Notizen

• To determine whether the measurable diffusion coefficient (MIC) may be used to differentiate normal and lymphomatosis-altered lymph nodes (LNs) in patients with Hodgkin lymphoma (HL). Whole-body magnetic resonance (MR) imaging was used to compare the MICs of LNs in 27 apparently healthy individuals and 41 patients with a verified diagnosis of HL. Construction of 95% confidence intervals showed that the MICs of normal LNs were in the range of 1.00 to 1.73 x x10(-3) mm2/sec and significantly higher (p < 0.05) than those of lymphomatosis-affected LNs (MIC, 0.59 to 0.94 x 10(-3) mm2/sec). The cut-off point (for discretization) of normal and lymphomatosis-altered LNs was in the range of 0.94 to 1.00 x 10(-3) mm2/sec. Consequently, the LN with a MIC of less than 0.94 x 10(-3) mm2/sec may be thought of as affected by the lymphomatous process. MIC calculation permits differentiation of normal and affected LNs having equal signal characteristics (including those on diffusion-weighted MR images).