Details
- Autor(en) / Beteiligte
- Titel
- Analysis of candidate genes for morphine preference quantitative trait locus Mop2
- Ist Teil von
- Neuroscience, 2014-09, Vol.277, p.403-416
- Ort / Verlag
- United States: Elsevier Ltd
- Erscheinungsjahr
- 2014
- Link zum Volltext
- Quelle
- ScienceDirect Journals (5 years ago - present)
- Beschreibungen/Notizen
- Highlights • Chr 10 morphine preference Mop2 QTL refined to 22 candidate genes. • Ppp1r14c mRNA does not differ among morphine-treated C57BL/6 and DBA/2 mice. • Differential mRNA expression of Iyd and Vip among C57BL/6 and DBA/2 mice. • Morphine increases Rgs17 mRNA, but not Rgs17 protein in the frontal cortex of DBA/2 and C57BL/6 mice. • Rgs17 protein levels differ between C57BL/6 and DBA/2 mice in Midbrain/Brainstem and Nucleus accumbens regions.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0306-4522eISSN: 1873-7544DOI: 10.1016/j.neuroscience.2014.07.020Titel-ID: cdi_pubmed_primary_25058503
- Format
- –
- Schlagworte
- Analgesics, Non-Narcotic - administration & dosage, Animals, Brain - physiology, Choice Behavior - drug effects, Choice Behavior - physiology, Drinking Behavior - drug effects, Drinking Behavior - physiology, Drug-Seeking Behavior - physiology, Gene Expression - physiology, IYD, Mice, Inbred C57BL, Mice, Inbred DBA, Morphine - administration & dosage, Narcotics - administration & dosage, Neurology, Ppp1r14c, Quantitative Trait Loci, Quinine - administration & dosage, RGS Proteins - metabolism, Rgs17, Species Specificity, two-bottle choice, Vip, μ-opioid receptor