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  • BibTeX
Montanide ISA™ 201 adjuvanted FMD vaccine induces improved immune responses and protection in cattle
Vaccine, 2013-07, Vol.31 (33), p.3327-3332
2013

Details

Autor(en) / Beteiligte
Titel
Montanide ISA™ 201 adjuvanted FMD vaccine induces improved immune responses and protection in cattle
Ist Teil von
  • Vaccine, 2013-07, Vol.31 (33), p.3327-3332
Ort / Verlag
Kidlington: Elsevier Ltd
Erscheinungsjahr
2013
Link zum Volltext
Quelle
Elsevier ScienceDirect Journals Complete
Beschreibungen/Notizen
  • Highlights • This study presents Montanide ISA-201 as superior adjuvant to inactivated FMD vaccine. • ISA-201 elicited higher clinical protection against FMDV exposure in cattle. • FMDV-specific neutralizing antibody and IgG1 /IgG2 responses were more robust. • Based on the lymphoproliferation and IgG1 /IgG2 , ISA-201 directed responses to TH 1. • Consequently, the post-challenge virus replication showed significant inhibition.
Sprache
Englisch
Identifikatoren
ISSN: 0264-410X
eISSN: 1873-2518
DOI: 10.1016/j.vaccine.2013.05.078
Titel-ID: cdi_pubmed_primary_23735678
Format
–
Schlagworte
Adjuvants, Adjuvants, Immunologic - administration & dosage, Allergy and Immunology, Animals, Antibodies, Neutralizing - blood, Antibodies, Viral - blood, antigens, Applied microbiology, Biological and medical sciences, blood serum, Cattle, Cattle - immunology, Cattle Diseases - immunology, Cattle Diseases - prevention & control, Cell Proliferation, Foot & mouth disease, foot-and-mouth disease, Foot-and-Mouth Disease - immunology, Foot-and-Mouth Disease - prevention & control, Foot-and-Mouth Disease Virus, Fundamental and applied biological sciences. Psychology, GAHOL, genome, immune response, Immunoglobulin G - blood, Injections, Intramuscular, Male, Medical research, Microbiology, Miscellaneous, Montanide ISA 201, Montanide ISA 206, neutralization, Neutralization Tests, neutralizing antibodies, Oil-adjuvants, oils, oropharynx, serology, Th1 Cells - immunology, Vaccination - veterinary, Vaccine, Vaccines, Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects), Vaccines, Inactivated - immunology, Vaccines, Inactivated - therapeutic use, Viral Vaccines - immunology, Viral Vaccines - therapeutic use, Virology, virus replication, viruses

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