Details

Autor(en) / Beteiligte

• Robaglia, Christophe
• Thomas, Martine
• Meyer, Christian

Titel

Sensing nutrient and energy status by SnRK1 and TOR kinases

Ist Teil von

• Current opinion in plant biology, 2012-06, Vol.15 (3), p.301-307

Ort / Verlag

Amsterdam: Elsevier Ltd

Erscheinungsjahr

2012

Link zum Volltext

Quelle

Elsevier ScienceDirect Journals Complete

Beschreibungen/Notizen

• ► The conserved TOR and SnRK1 protein kinases are central hubs coordinating cellular adaptations to changes in nutrient and energy status. ► Many conserved elements of the TOR and SnRK1 signaling pathways exist in plants and play roles which have been probably more or less adapted to the plants’ specific needs. ► In yeast and animals, the TOR and Snf1/AMPK protein kinases have antagonistic roles in adjusting several cellular processes like autophagy. ► It will be important to determine how the TOR signaling pathway interacts in plants with that of SnRK1. The perception of nutrient and energy levels inside and outside the cell is crucial to adjust growth and metabolism to available resources. The signaling pathways centered on the conserved TOR and SnRK1/Snf1/AMPK kinases have crucial and numerous roles in nutrient and energy sensing and in translating this information into metabolic and developmental adaptations. In plants evidence is mounting that, like in other eukaryotes, these signaling pathways have pivotal and antagonistic roles in connecting external or intracellular cues to many biological processes, including ribosome biogenesis, regulation of translation, cell division, accumulation of reserves and autophagy. Data on the plant TOR pathway have been hitherto rather scarce but recent findings have shed new light on its roles in plants. Moreover, the distinctive energy metabolism of photosynthetic organisms may reveal new features of these ancestral eukaryotic signaling elements.