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Permeability evaluation of 45S5 Bioglass® -based scaffolds for bone tissue engineering
Ist Teil von
Journal of biomechanics, 2009-02, Vol.42 (3), p.257-260
Ort / Verlag
United States: Elsevier Ltd
Erscheinungsjahr
2009
Link zum Volltext
Quelle
Elsevier ScienceDirect Journals Complete
Beschreibungen/Notizen
Abstract Permeability is a key parameter for microstructural design of scaffolds, since it is related to their capability for waste removal and nutrients/oxygen supply. In this framework, Darcy's experiments were carried out in order to determine the relationship between the pressure drop gradient and the fluid flow velocity in Bioglass® -based scaffolds to obtain the scaffold's permeability. Using deionised water as working fluid, the measured average permeability value on scaffolds of 90–95% porosity was 1.96×10−9 m2 . This value lies in the published range of permeability values for trabecular bone.