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This article offers a situated overview of the work of Anselm Strauss. Beginning from its intellectual genesis at the University of Chicago with Blumer and Hughes, Strauss's creation of a sociology of action through concepts of routine and nonroutine action, negotiated order, social worlds, arenas, properties and kinds of work, and trajectory are examined. Strauss's ideas about medicine and chronic illness, psychiatric institutions, death and dying, awareness contexts, biography and trajectory are discussed. His profoundly innovative contributions to research methods, including grounded theory and the integration of structural elements through his conditional matrix, are also detailed. In conclusion, the ways in which Strauss himself framed the critical space of an interactionist sociologist are laid out through new interview materials.