Details

Autor(en) / Beteiligte

• Fasano, Alfonso
• Cereda, Emanuele
• Barichella, Michela
• Cassani, Erica
• Ferri, Valentina
• Zecchinelli, Anna Lena
• Pezzoli, Gianni

Titel

COVID‐19 in Parkinson’s Disease Patients Living in Lombardy, Italy

Ist Teil von

• Movement disorders, 2020-07, Vol.35 (7), p.1089-1093

Ort / Verlag

Hoboken, USA: John Wiley & Sons, Inc

Erscheinungsjahr

2020

Quelle

Wiley-Blackwell Journals

Beschreibungen/Notizen

• Background It is unknown whether patients with PD are at greater risk of COVID‐19, what their risk factors are, and whether their clinical manifestations differ from the general population. Objectives The study aimed to address all these issues. Methods In a case‐controlled survey, we interviewed 1,486 PD patients attending a single tertiary center in Lombardy, Italy and 1,207 family members (controls). Results One hundred five (7.1%) and 92 controls (7.6%) were identified as COVID‐19 cases. COVID‐19 patients were younger, more likely to suffer from chronic obstructive pulmonary disease, to be obese, and vitamin D nonsupplemented than unaffected patients. Six patients (5.7%) and 7 family members (7.6%) died from COVID‐19. Patients were less likely to report shortness of breath and require hospitalization. Conclusions In an unselected large cohort of nonadvanced PD patients, COVID‐19 risk and mortality did not differ from the general population, but symptoms appeared to be milder. The possible protective role of vitamin D supplementation warrants future studies. © 2020 International Parkinson and Movement Disorder Society