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Small (< 4 cm) Bosniak renal cysts: association of initial fluid percentage and enhancing solid volume thresholds with future lesion behavior
Ist Teil von
Abdominal radiology (New York), 2020-03, Vol.45 (3), p.799-806
Ort / Verlag
New York: Springer US
Erscheinungsjahr
2020
Link zum Volltext
Quelle
SpringerNature Journals
Beschreibungen/Notizen
Purpose
Evaluate the fluid percentage (FP) and enhancing solid volume (SV) of small (< 4 cm) Bosniak 2F, 3 and 4 renal lesions and the association with Bosniak category at baseline and follow-up.
Methods
Hospital database was searched from 1/1/2010 to 8/3/2018 for small (< 4 cm) Bosniak 2F, 3 and 4 lesions studied with initial and follow-up C+CT/MRI. Two radiologists blindly assigned Bosniak categories to first and last available studies. One radiologist performed volumetric analysis of each lesion, calculating the FP and SV. Association with Bosniak category was explored.
Results
121 patients (84:37 M:F) were identified with 136 renal lesions (84, 37 and 15 Bosniak category 2F, 3 and 4) and followed for 1–12.3 years (mean 3.5 years). 87% (73/84) of 2F lesions were downgraded or remained stable. 48% (25/52) of 3/4 lesions were downgraded. Higher FP was associated with a lower Bosniak category (
p
value = 0.0042). Increase in FP was associated with the probability of being downgraded on follow-up (OR 1.03,
p
value = 0.0036), while increase in fluid volume of lesion was directly associated with change in overall lesion size among lesions that were downgraded (b-estimate = 0.03,
p
value = 0.0003). All Bosniak 3/4 lesions with initial SV less than 0.05 cc were downgraded.
Conclusion
FP and SV are useful quantitative surrogates for Bosniak category and future behavior, respectively. Growth of small renal lesions by an increase in fluid volume and FP leads to a downgrade in Bosniak category. Initial SV less than 0.05 cc in Bosniak 3/4 lesions suggests possible future downgrade.