Details

Autor(en) / Beteiligte

• Zhang, Shan
• Wu, Chun
• Zhang, Zunting
• Wang, Tao

Titel

Metal-Free Synthesis of 3‑(Iso)quinolinyl 4‑Chromenones and 3‑(Iso)quinolinyl 4-Quinolones from (Iso)quinoline N‑Oxides and Ynones

Ist Teil von

• Organic letters, 2019-12, Vol.21 (24), p.9995-9998

Ort / Verlag

United States: American Chemical Society

Erscheinungsjahr

2019

Link zum Volltext

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• A general approach for the synthesis of 3-(iso)­quinolinyl 4-chromenones and 3-(iso)­quinolinyl 4-quinolones from (iso)­quinoline N-oxides and ynones under metal-free conditions was developed. The reaction of (iso)­quinoline N-oxide with the electron-deficient alkyne first generated an (iso)­quinolinyl β-diketone intermediate, which then underwent an intramolecular dehydration, affording 3-(iso)­quinolinyl 4-chromenones and 3-(iso)­quinolinyl 4-quinolones.