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Omadacycline for Acute Bacterial Skin and Skin-Structure Infections
The New England journal of medicine, 2019-02, Vol.380 (6), p.528-538
2019

Details

Autor(en) / Beteiligte
Titel
Omadacycline for Acute Bacterial Skin and Skin-Structure Infections
Ist Teil von
  • The New England journal of medicine, 2019-02, Vol.380 (6), p.528-538
Ort / Verlag
United States: Massachusetts Medical Society
Erscheinungsjahr
2019
Link zum Volltext
Quelle
Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals
Beschreibungen/Notizen
  • Treatment for acute bacterial skin and skin-structure infections is becoming more challenging as organisms with antimicrobial resistance become more prevalent. In this randomized trial involving 655 adults with bacterial skin and skin-structure infections, omadacycline was noninferior to linezolid regardless of the causative pathogen, including MRSA.
Sprache
Englisch
Identifikatoren
ISSN: 0028-4793
eISSN: 1533-4406
DOI: 10.1056/NEJMoa1800170
Titel-ID: cdi_proquest_miscellaneous_2186146808
Format
–
Schlagworte
Adolescent, Adult, Aged, Aged, 80 and over, Anti-Bacterial Agents - adverse effects, Anti-Bacterial Agents - therapeutic use, Antibiotic resistance, Antibiotics, Bacteria, Clinical trials, Double-Blind Method, Drug Administration Schedule, Drug dosages, Drug resistance, Drug Resistance, Bacterial, Female, Gram-positive bacteria, Humans, Infusions, Intravenous, Intention to Treat Analysis, Linezolid, Linezolid - adverse effects, Linezolid - therapeutic use, Male, Methicillin, Methicillin-Resistant Staphylococcus aureus - drug effects, Middle Aged, Morbidity, Patients, Pharmaceuticals, Skin, Skin Diseases, Bacterial - drug therapy, Skin Diseases, Bacterial - microbiology, Staphylococcus infections, Statistical analysis, Substance abuse treatment, Survival, Tetracyclines - adverse effects, Tetracyclines - therapeutic use, Ulcers, Young Adult

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