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Association of serum procalcitonin level with in-stent restenosis in patients undergoing bare-metal stent implantation
Ist Teil von
Biomarkers in medicine, 2018-05, Vol.12 (5), p.455-463
Ort / Verlag
England: Future Medicine Ltd
Erscheinungsjahr
2018
Quelle
MEDLINE
Beschreibungen/Notizen
Procalcitonin (PCT) is an inflammatory marker and elevated PCT levels are associated with cardiovascular events. We assessed whether PCT level is an independent predictor of bare-metal stent (BMS) in-stent restenosis (ISR).
We evaluated 240 patients undergoing BMS implantation. Serum PCT levels were measured before procedure. Patients were classified as ISR(-) group (n = 120) and ISR(+) group (n = 120).
Serum PCT levels were higher in the ISR (+) group (p < 0.001). At multivariate analysis, PCT (odds ratio [OR] 1.561; p = 0.012), stent length (OR: 1.089), stent diameter (OR: 0.141) and uric acid (OR: 1.465) were independent predictors of ISR.
Serum PCT is independently associated with ISR and increased PCT levels may provide useful information for the risk of BMS-ISR.