Details

Autor(en) / Beteiligte

• Broos, Caroline E
• Wapenaar, Monique
• Looman, Caspar W N
• In 't Veen, Johannes C C M
• van den Toorn, Leon M
• Overbeek, Maria J
• Grootenboers, Marco J J H
• Heller, Roxane
• Mostard, Rémy L
• Poell, Linda H C
• Hoogsteden, Henk C
• Kool, Mirjam
• Wijsenbeek, Marlies S
• van den Blink, Bernt

Titel

Daily home spirometry to detect early steroid treatment effects in newly treated pulmonary sarcoidosis

Ist Teil von

• The European respiratory journal, 2018-01, Vol.51 (1), p.1702089-1702089

Ort / Verlag

England: European Respiratory Society Journals Ltd

Erscheinungsjahr

2018

Link zum Volltext

Quelle

EZB-FREE-00999 freely available EZB journals

Beschreibungen/Notizen

• Prednisone is the mainstay of sarcoidosis treatment. However, prednisone treatment optimisation is warranted, since prolonged high-dose prednisone therapy is associated with burdensome and harmful side-effects [1, 2]. Early prednisone dose tapering has the potential to reduce side-effects. Gaining insight in the early treatment response can help to determine when tapering could be initiated. To date, there are no prospective studies that look at early treatment response to prednisone in sarcoidosis by monitoring clinical symptoms and daily patient-administered lung function. Therefore, we initiated a multicentre, prospective and observational study with daily home spirometry to detect early steroid treatment effects in newly treated pulmonary sarcoidosis (Dutch National Trial Register NTR4328; www.trialregister.nl/trialreg).