Details

Autor(en) / Beteiligte

• Meloche, Jennifer L.
• Ashfeld, Brandon L.

Titel

A Rhodium(II)‐Catalyzed Formal [4+1]‐Cycloaddition toward Spirooxindole Pyrrolone Construction Employing Vinyl Isocyanates as 1,4‐Dipoles

Ist Teil von

• Angewandte Chemie (International ed.), 2017-06, Vol.56 (23), p.6604-6608

Auflage

International ed. in English

Ort / Verlag

Germany: Wiley Subscription Services, Inc

Erscheinungsjahr

2017

Link zum Volltext

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• A RhII‐catalyzed, formal [4+1]‐cycloaddition between diazooxindoles as electrophilic C1 synthons and 1,3‐heterodienes for the construction of spirooxindole pyrrolones is described. Employing vinyl isocyanates as 1,4‐dipoles, the cycloannulation occurs under relatively mild conditions and provides the corresponding pyrrolones in good to excellent yields. Put a ring on it: The title reaction between diazooxindoles as electrophilic C1 synthons and 1,3‐heterodienes enables the construction of spirooxindole pyrrolones. Employing vinyl isocyanates as 1,4‐dipoles, the cycloannulation occurs under relatively mild conditions and provides the corresponding pyrrolones in good to excellent yields.