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Cancer screening via infrared spectral cytopathology (SCP): results for the upper respiratory and digestive tracts
Ist Teil von
Analyst (London), 2016-01, Vol.141 (2), p.416-428
Ort / Verlag
England
Erscheinungsjahr
2016
Link zum Volltext
Quelle
Alma/SFX Local Collection
Beschreibungen/Notizen
Instrumental advances in infrared micro-spectroscopy have made possible the observation of individual human cells and even subcellular structures. The observed spectra represent a snapshot of the biochemical composition of a cell; this composition varies subtly but reproducibly with cellular effects such as progression through the cell cycle, cell maturation and differentiation, and disease. The aim of this summary is to provide a synopsis of the progress achieved in infrared spectral cytopathology (SCP) - the combination of infrared micro-spectroscopy and multivariate methods of analysis - for the detection of abnormalities in exfoliated human cells of the upper respiratory and digestive tract, namely the oral and nasopharyngeal cavities, and the esophagus.
Instrumental advances in infrared micro-spectroscopy have made possible the observation of individual human cells and even subcellular structures.