Details

Autor(en) / Beteiligte

• Kotta-Loizou, Ioly
• Karakasiliotis, Ioannis
• Vassilaki, Niki
• Sakellariou, Panagiotis
• Bartenschlager, Ralf
• Mavromara, Penelope
• Ou, J.-H. J.

Titel

Expression of the novel hepatitis C virus core+1/ARF protein in the context of JFH1-based replicons

Ist Teil von

• Journal of virology, 2015-05, Vol.89 (9), p.5164-5170

Ort / Verlag

United States: American Society for Microbiology

Erscheinungsjahr

2015

Link zum Volltext

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• Hepatitis C virus contains a second open reading frame within the core gene, designated core+1/ARF. Here we demonstrate for the first time expression of core+1/ARF protein in the context of a bicistronic JFH1-based replicon and report the production of two isoforms, core+1/L (long) and core+1/S (short), with different kinetics.