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Acute Coronary Syndrome Antiplatelet Alternatives in Clopidogrel Allergy
Ist Teil von
Pharmacotherapy, 2014-08, Vol.34 (8), p.e152-e156
Ort / Verlag
United States: Wiley Subscription Services, Inc
Erscheinungsjahr
2014
Link zum Volltext
Quelle
Alma/SFX Local Collection
Beschreibungen/Notizen
No published information exists to support the safe use of ticagrelor in patients with a clopidogrel allergy. This study involved an institutional review board–approved retrospective review of patients with a documented clopidogrel allergy who subsequently received ticagrelor between July 2011 and February 2014. We report the cases of two patients with a history of hypersensitivity to clopidogrel in whom ticagrelor was used successfully without documented incident. In addition, principles suggesting a lack of cross‐sensitivity between ticagrelor and clopidogrel are reviewed. These cases combined with theoretical evidence support the use of ticagrelor in patients with hypersensitivity to clopidogrel.