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Beyond microRNA – Novel RNAs derived from small non-coding RNA and their implication in cancer
Cancer letters, 2013-11, Vol.340 (2), p.201-211
2013

Details

Autor(en) / Beteiligte
Titel
Beyond microRNA – Novel RNAs derived from small non-coding RNA and their implication in cancer
Ist Teil von
  • Cancer letters, 2013-11, Vol.340 (2), p.201-211
Ort / Verlag
Ireland: Elsevier Ireland Ltd
Erscheinungsjahr
2013
Link zum Volltext
Quelle
Elsevier ScienceDirect Journals Complete
Beschreibungen/Notizen
  • Highlights ► SnoRNAs and tRNAs are specifically processed to different, functional types of smaller RNAs referred to as sdRNAs and tRFs. ► The expression of many snoRNAs, tRNAs, and derived from them smaller RNAs is altered in human disease and cancer. ► SdRNAs and tRFs share components of the molecular pathways of RNAi and may function in gene regulation or stress signaling. ► SnoRNAs, tRNAs, and derived from them smaller RNAs are potential oncogenes or tumor suppressor genes. ► SdRNAs and tRFs may provide new perspectives for the development of novel biomarkers and therapeutic strategies in cancer.
Sprache
Englisch
Identifikatoren
ISSN: 0304-3835
eISSN: 1872-7980
DOI: 10.1016/j.canlet.2012.11.058
Titel-ID: cdi_proquest_miscellaneous_1459558097
Format
–
Schlagworte
Animals, Apoptosis, Biomarkers, Tumor - genetics, Cancer, Cell growth, Deoxyribonucleic acid, DNA, DNA methylation, Evolution, Molecular, Gene expression, Gene Expression Profiling, Gene Expression Regulation, Neoplastic, Genetic Predisposition to Disease, Genetic Testing, Genome, Human, Genomes, Genomics - methods, Hematology, Oncology and Palliative Medicine, High-Throughput Nucleotide Sequencing, Humans, microRNA, MicroRNAs, MicroRNAs - metabolism, Mitochondrial DNA, Neoplasms - diagnosis, Neoplasms - genetics, Neoplasms - therapy, Next generation sequencing, Non-coding RNA, Oligonucleotide Array Sequence Analysis, Phenotype, Predictive Value of Tests, Prognosis, Proteins, RNA polymerase, RNA, Neoplasm - metabolism, RNA, Small Nucleolar - metabolism, RNA, Small Untranslated - metabolism, RNA, Transfer - metabolism, Sequence Analysis, RNA, snoRNA-derived RNA (sdRNA), Technological change, Telomerase, transcriptome, Transfer RNA, tRNA fragment (tRF)

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