Details

Autor(en) / Beteiligte

• Xue, Hui
• Wang, Jiaru
• Xu, Wanting
• Zhang, Yi
• Luo, Yinghua
• Jin, Chenghao

Titel

Pharmacological Mechanism of Isoliquiritigenin Antitumor

Ist Teil von

• Medicinal plant, 2019-02, Vol.10 (1), p.17-18

Ort / Verlag

Cranston: Wu Chu (USA-China) Science and Culture Media Corporation

Erscheinungsjahr

2019

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Since ISL has extensive antitumor activity and clear mechanism, and modifier activity enhances, it has development potential of new antitumor drugs'5 7' , and its antitumor activity has become research hotspots. The research aims to provide theoretical basis for studying antitumor activity of ISL and developing new anticancer drugs. 2 Antineoplastic pathway 2.1 Inhibiting proliferation of cancer cells ISL could inhibit proliferation of multiple cancer cells, containing cervical cancer, breast cancer, lung cancer and pancreatic cancer. Research displays that changes of genes related to apoptosis affect tumorigenesis. [...]important strategy of oncotlierapy is inducing apoptosis of tumor cells'12'. ISL could play the effect of antitumor by inhibiting proliferation of cancer cell, inducing apoptosis of cancer cells and resisting tumor angiogenesis, further avoiding single action mechanism and human body prone to drug resistance.