Details

Autor(en) / Beteiligte

• Iber, Dagmar
• Menshykau, Denis

Titel

The control of branching morphogenesis

Ist Teil von

• Open biology, 2013-09, Vol.3 (9), p.130088-130088

Ort / Verlag

England: The Royal Society

Erscheinungsjahr

2013

Link zum Volltext

Quelle

EZB Free E-Journals

Beschreibungen/Notizen

• Many organs of higher organisms are heavily branched structures and arise by an apparently similar process of branching morphogenesis. Yet the regulatory components and local interactions that have been identified differ greatly in these organs. It is an open question whether the regulatory processes work according to a common principle and how far physical and geometrical constraints determine the branching process. Here, we review the known regulatory factors and physical constraints in lung, kidney, pancreas, prostate, mammary gland and salivary gland branching morphogenesis, and describe the models that have been formulated to analyse their impacts.