Details

Autor(en) / Beteiligte

• Fardin, Rafaela Barbirato
• Leite, Luiz Arhur Calheiros
• Bezerra, Luanna Mayara Dos Santos
• Alves, Priscilla Maris Pereira
• Dos Santos, Layanne Lima
• Salvá, Marília de Andrade
• Rezende Filho, Antônio Luiz Soares Moura
• Lima, Gilberto Salustiano
• Matos, Juliana de Amorim
• Ferreira, Sônia Maria Soares
• Costa, Ducy Lily Joazeiro de Farias

Titel

Fatal Disseminated Kaposi's Sarcoma in Two Patients with Human Immunodeficiency Virus (HIV) InfectionFatal Disseminated Kaposi's Sarcoma in Two Patients with Human Immunodeficiency Virus (HIV) Infection

Ist Teil von

• The American journal of case reports, 2018-07, Vol.19, p.868-874

Ort / Verlag

United States

Erscheinungsjahr

2018

Link zum Volltext

Quelle

Electronic Journals Library - Freely accessible e-journals

Beschreibungen/Notizen

• BACKGROUND Kaposi's sarcoma (KS) is a common condition in patients with human immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome (AIDS). In these patients, the occurrence of KS is reduced by treatment with highly active antiretroviral therapy (HAART). Fatal and disseminated KS is presented in two patients with HIV/AIDS. CASE REPORT A 25-year-old man and a 30-year-old man with HIV/AIDS presented with KS affecting the skin, oral cavity, gastrointestinal tract, liver, lungs, kidneys, adrenal glands, and bone. Both patients had a rapidly deteriorating clinical course associated with a low CD4 count and developed respiratory failure and death. CONCLUSIONS Fatal disseminated KS is associated with severe immunosuppression due to with a low CD4 count. The presentation of these two cases highlights the potentially aggressive clinical course of KS in patients with HIV/AIDS and reinforces the need for early diagnosis and rapid treatment with HAART.