Details

Autor(en) / Beteiligte

• Timin, Alexander S.
• Khashirova, S. Yu
• Zhansitov, Azamat
• Rumyantsev, E. V.

Titel

Synthesis and application of silica hybrids grafted with new guanidine-containing polymers as highly effective adsorbents for bilirubin removal

Ist Teil von

• Colloid and polymer science, 2015-06, Vol.293 (6), p.1667-1674

Ort / Verlag

Berlin/Heidelberg: Springer Berlin Heidelberg

Erscheinungsjahr

2015

Quelle

Springer Nature - Complete Springer Journals

Beschreibungen/Notizen

• The development and design of adsorbents with high adsorption performance is the actual aim for successful toxin removal. In this work, we report the performance of new guanidine-containing polymers as a shell orientated around silica particles with following application for effective bilirubin removal. To evaluate polymer-shell modification, Fourier transform infrared spectroscopy and high-resolution electron microscopy were performed. Changes in surface morphology of polymer-coated silicas were detected. It was shown that polymeric shell completely covers silica surface. The grafting amount was evaluated by thermogravimetric and was in 18–34 % range. Incorporation of guanidine containing polymers into silica matrix leads to the great increase in adsorption capacity According to the Langmuir model, the maximum adsorption capacity for bilirubin was 43.47 mg/g. We also demonstrated that prepared polymer-coated silicas could well adsorb bilirubin from the bilirubin-albumin solution at low concentration of albumin. Therefore, this study revealed that guanidine-containing polymers have great potential to serve as effective agents for improving of the adsorbent for bilirubin removal. Graphical Abstract ᅟ