Details

Autor(en) / Beteiligte

• Bruijn, F. J. de

Titel

Stress and environmental regulation of gene expression and adaptation in bacteria

Ort / Verlag

Hoboken, New Jersey : Wiley-Blackwell,

Erscheinungsjahr

2016

Link zum Volltext

• Wiley Online Library - AutoHoldings Books

Beschreibungen/Notizen

• Description based upon print version of record.
• Includes bibliographical references at the end of each chapters and index.
• Stress and environmental regulation of gene expression and adaptation in bacteria; Contents; Preface; Acknowledgements; List of contributors; 1 Introduction; 2 Key overview chapters; 2.1 Stress-induced changes in transcript stability; 2.1.1 Introduction; 2.1.2 RNA chaperones - cold shock proteins; 2.1.3 Stability of the general stress transcripts; 2.1.4 Stress-induced change in transcript stability of heat shock response genes; 2.1.5 Physiological consequences of the decreased stability of heat shock gene transcripts; 2.1.6 The physiological roles of CspC and CspE; 2.1.7 Conclusions
• 2.1.8 Open questionsReferences; 2.2 StressChip for monitoring microbial stress response in the environment; 2.2.1 Introduction; 2.2.2 Microarrays; 2.2.3 Functional gene microarrays; 2.2.4 The StressChip FGA; 2.2.4.1 Design overview; 2.2.4.2 General microarray qualities; 2.2.4.3 StressChip design; 2.2.4.4 Gene selection; 2.2.4.5 Evaluation of StressChip; 2.2.5 GeoChip data analysis pipeline; 2.2.6 Conclusion and summary; Acknowledgements; References; 2.3 A revolutionary paradigm of bacterial genome regulation; 2.3.1 Introduction
• 2.3.2 RNA polymerase sigma factors: search for recognition of target promoters2.3.3 Transcription factors (TFs): search invivo for regulation targets using transcriptome and ChIP-chip analyses; 2.3.4 Transcription factors (TFs): search invitro for regulation targets using the Genomic SELEX screening system; 2.3.5 Functional classification of TFs; 2.3.6 Level control of TFs; 2.3.7 Activity control of TFs; 2.3.8 Promoter-specific (PS)-TF screening; 2.3.9 Hierarchical networks of TF-TF interplays; Acknowledgements; References
• 2.4 Role of changes in 70-driven transcription in adaptation of E.coli to conditions of stress or starvation2.4.1 Introduction; 2.4.2 Sigma factors compete for binding to core RNAP; 2.4.3 Reallocation of RNAP to maintenance-related promoters during stress and starvation; 2.4.4 Rsd: An Anti-70 protein; 2.4.4.1 Rsd promotes transcription by alternative sigma factors; 2.4.4.2 Mechanism of inhibition of 70-driven transcription by Rsd; 2.4.5 6S RNA: a transcription-regulating small RNA; 2.4.5.1 6S RNA and survival of E. coli during the late stationary phase
• 2.4.5.2 6S RNA inhibits 70-mediated transcription2.4.5.3 6S RNA competes with -35 promoter region for binding to region 4.2 of 70; 2.4.6 (p)ppGpp, DksA and CarD regulate transcription; 2.4.6.1 (p)ppGpp, DksA and CarD interact with RNAP; 2.4.6.2 Complementary and opposing effects of (p)ppGpp and DksA; 2.4.6.3 Presence of (p)ppGpp or DksA favors transcription driven by alternate sigma factors; 2.4.7 Concluding remarks; Acknowledgements; References; 2.5 The distribution and spatial organization of RNA polymerase in Escherichia coli: growth rate regulation and stress responses
• 2.5.1 Introduction
• English
• Description based on print version record.