Details

Autor(en) / Beteiligte

• Piemonte, Vincenzo,

Titel

Biomedical engineering challenges : a chemical engineering insight

Auflage

1st ed

Ort / Verlag

Hoboken, New Jersey : Wiley,

Erscheinungsjahr

2018

Beschreibungen/Notizen

• Includes bibliographical references at the end of each chapters and index.
• Intro -- Title Page -- Copyright Page -- Contents -- List of Contributors -- Preface -- Chapter 1 Introduction -- References -- Chapter 2 Artificial Kidney: The New Challenge -- 2.1 Introduction -- 2.2 Kidney Transplantation Statistics -- 2.3 Transplantation Costs -- 2.4 Post-Transplant Costs -- 2.5 Renal Replacement Devices -- 2.6 Implantable Artificial Kidney: Prototype Developments -- 2.7 Kidney Tissue Engineering -- 2.8 Next Steps -- 2.9 Conclusion -- List of Acronyms -- References -- Chapter 3 Current Status and New Challenges of the Artificial Liver -- 3.1 Introduction -- 3.2 Non-Biological Artificial Liver -- 3.2.1 Classification and Clinical Study -- 3.2.2 PE and HDF -- 3.2.2.1 High-Volume Therapeutic PE -- 3.2.2.2 High-Flow Dialysate Continuous HDF -- 3.2.2.3 PE with Online HDF -- 3.2.3 Blood Purification with Albumin Dialysis -- 3.2.3.1 Single-Pass Albumin Dialysis -- 3.2.3.2 Molecular Adsorbent Recirculating System -- 3.2.3.3 Fractionated Plasma Separation and Adsorption (Prometheus™) -- 3.2.3.4 Hepa Wash -- 3.2.4 Selective Plasma Filtration Therapy -- 3.2.4.1 Biologic-Detoxifilter/Plasma Filter -- 3.2.4.2 Selective Plasma-Exchange Therapy -- 3.2.4.3 Plasma Filtration with Dialysis -- 3.2.5 Clinical Observations of Various Combinations -- 3.3 Bioartificial Liver -- 3.3.1 Bioartificial Liver Support System -- 3.3.2 Cell Source for BAL -- 3.4 New Stream for Artificial Liver -- 3.4.1 Tissue Engineering for Liver Construction -- 3.4.2 Whole Organ Engineering for the Transplantable Artificial Liver -- 3.5 Conclusion and Future Trends -- List of Acronyms -- References -- Chapter 4 A Chemical Engineering Perspective on Blood Oxygenators -- 4.1 Introduction -- 4.2 A Historical Note -- 4.3 Chemical Engineering Principles in Blood Oxygenators -- 4.4 Chemical Engineering Process Analogues of ECMO Systems -- 4.5 New Challenges -- 4.6 Conclusion.
• List of Symbols -- References -- Chapter 5 Model Predictive Control for the Artificial Pancreas -- 5.1 Introduction -- 5.2 Phenomenological Models -- 5.2.1 Background and Two-Compartmental Models -- 5.2.2 Three-Compartment Models -- 5.3 Black-Block Approach -- 5.4 Conclusions -- Nomenclature -- Acronyms and Variables -- Greek Letters -- References -- Chapter 6 Multiscale Synthetic Biology: From Molecules to Ecosystems -- 6.1 Introduction: An Historical‐Epistemological Perspective -- 6.2 Applications -- 6.2.1 Protein Synthetic Biology -- 6.2.2 Tissue Engineering and Artificial Organs -- 6.2.3 Biotechnology and Ecology Applications -- 6.3 Conclusions -- List of Symbols -- References -- Chapter 7 Chemical Reaction Engineering Methodologies for Biomedical Imaging Analysis -- 7.1 Introduction -- 7.2 Magnetic Resonance Imaging (MRI) -- 7.2.1 1H-MRI -- 7.2.2 19F-MRI -- 7.2.3 MRI using Magnetization Transfer -- 7.3 Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) -- 7.3.1 PET -- 7.3.2 SPECT -- 7.4 Fluorescence Imaging -- 7.4.1 Fluorescent Proteins -- 7.4.2 Small Organic Fluorophores -- 7.5 Conclusion -- List of Abbreviations -- References -- Chapter 8 Noninvasive and Label‐Free Characterization of Cells for Tissue Engineering Purposes -- 8.1 Introduction -- 8.2 Multivariate Analyses -- 8.2.1 Principal Component Analysis (PCA) -- 8.2.2 Linear Discriminant Analysis (LDA) -- 8.2.3 Hierarchical Clustering Analysis (HCA) -- 8.2.4 Other Multivariate Analyses -- 8.3 Vibrational Spectroscopic Features -- 8.3.1 Cell Characterization Based on Whole-Cell Analysis by Raman Spectroscopy -- 8.3.2 Cell Characterization Based on Subcellular Analysis by Raman Spectroscopy -- 8.3.3 Raman-Based Cell Characterization Toward Biomedical Applications -- 8.4 Morphological Features.
• 8.4.1 Cell Characterization Based on Unstained Microscopic Images of Single Cells -- 8.4.2 Cell Characterization Based on Unstained Microscopic Images of Cell Populations -- 8.5 Secreted Molecule Features -- 8.5.1 Cell Characterization Based on Response Signatures -- 8.6 Conclusion and Outlook -- List of Acronyms -- References -- Chapter 9 TMS-EEG: Methods and Challenges in the Analysis of Brain Connectivity -- 9.1 Introduction -- 9.1.1 Transcranial Magnetic Stimulation -- 9.1.2 Electroencephalography -- 9.1.3 Combined TMS and Electroencephalography -- 9.1.4 Data Acquisition -- 9.1.5 Artifacts and Their Prevention -- 9.2 Signal Processing Methods -- 9.2.1 Preprocessing -- 9.2.2 Connectivity Analysis Methods in TMS-EEG -- 9.2.3 Time Domain Methods -- 9.2.4 Frequency Domain Methods -- 9.3 TMS-EEG Applications in Studies of Connectivity -- 9.3.1 General Aspects -- 9.3.2 TMS-Evoked Potentials (TEPs) -- 9.3.3 TMS-Induced Oscillations -- 9.3.4 Clinical Perspectives -- 9.3.4.1 Alzheimer's Disease -- 9.3.4.2 Schizophrenia -- 9.3.4.3 Disorders of Consciousness -- 9.4 Conclusions and Future Trends -- List of Acronyms -- References -- Chapter 10 Thermal Treatments of Tumors: Principles and Methods -- 10.1 Introduction -- 10.2 Effects of Temperature on Living Tissue -- 10.2.1 Hyperthermal Tissue Destruction -- 10.2.2 Cold Temperature for Tissue Destruction -- 10.3 Physical Principles of Thermal Treatments -- 10.3.1 Hyperthermal Treatments -- 10.3.1.1 High-Intensity Focused Ultrasound Ablation -- 10.3.1.2 Radiofrequency Ablation (RFA) -- 10.3.1.3 Microwave Ablation (MWA) -- 10.3.1.4 Laser Ablation (LA) -- 10.3.2 Cryoablation -- 10.4 Mathematical Modeling of Thermal Therapies -- 10.5 Temperature Monitoring During Thermal Treatments -- 10.5.1 Invasive (Contact) Thermometric Techniques -- 10.5.2 Non-Invasive (Contactless) Thermometric Techniques -- 10.6 Conclusions.
• List of Acronyms -- List of Symbols -- References -- Index -- Supplemental Images -- EULA.
• "An important resource that puts the focus on the chemical engineering aspects of biomedical engineering In the past 50 years remarkable achievements have been advanced in the fields of biomedical and chemical engineering. With contributions from leading chemical engineers, Biomedical Engineering Challenges reviews the recent research and discovery that sits at the interface of engineering and biology. The authors explore the principles and practices that are applied to the ever-expanding array of such new areas as gene-therapy delivery, biosensor design, and the development of improved therapeutic compounds, imaging agents, and drug delivery vehicles. Filled with illustrative case studies, this important resource examines such important work as methods of growing human cells and tissues outside the body in order to repair or replace damaged tissues. In addition, the text covers a range of topics including the challenges faced with developing artificial lungs, kidneys, and livers; advances in 3D cell culture systems; and chemical reaction methodologies for biomedical imagining analysis. This vital resource: Covers interdisciplinary research at the interface between chemical engineering, biology, and chemistry Provides a series of valuable case studies describing current themes in biomedical engineering Explores chemical engineering principles such as mass transfer, bioreactor technologies as applied to problems such as cell culture, tissue engineering, and biomedical imaging Written from the point of view of chemical engineers, this authoritative guide offers a broad-ranging but concise overview of research at the interface of chemical engineering and biology"--
• Description based on print version record.