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Evidence-based Oncology; Contents; Contributors; Preface; Abbreviations; Levels of evidence and grades of recommendation; Section I: Principles and practice of "critical appraisal"; 1 Appraising clinical literature in cancer; 2 Finding the "best evidence" for cancer care; 3 Understanding the concepts behind health economics; 4 Stringent application of epidemiological criteria changes the interpretation of the effects of immunotherapy in advanced renal cell cancer; Section II: Cancer prevention; Preface; 5 Which interventions help individuals to stop smoking?; 6 Breast cancer prevention trials
7 Is cancer risk reduced by a health-enhancing diet? 8 Is cancer risk reduced by the intake or supplementation of retinoids and carotenoids?; 9 Do primary and secondary prevention interventions for sun protection reduce the risk of skin cancers?; 10 Do sunscreens reduce the incidence of skin cancers?; 11 Can lifestyle behaviour change reduce the risk and incidence of urological cancers?; 12 What is the role of prophylactic surgery in the prevention of colorectal cancer?; Section III: Screening for cancers; 13 Screening for breast cancer; 14 Cervical screening; 15 Screening for prostate cancer
16 Screening for ovarian cancer 17 Screening for colorectal cancer; 18 Screening for lung cancer; 19 Screening for stomach cancer; 20 Screening for melanoma; Section IV: Treating tumours of the respiratory system; 21 Lung cancer; 22 Malignant pleural mesothelioma; Section V: Treating tumours of the gastrointestinal tract; 23 Cancer of the oesophagus; 24 Gastric carcinoma; 25 Pancreatic cancer; 26 Hepatobiliary cancers; 27 The treatment of cancers of the small bowel; 28 The treatment of carcinoma of the colon and rectum; 29 Treatment of anal cancer
Section VI: Treating tumours of the urogenital system 30 Kidney cancer; 31 Cancer of the bladder; 32 Cancer of the prostate; 33 Cancer of the penis; 34 Testicular germ cell cancer; Section VII: Treating gynaecological tumours; 35 Ovarian and fallopian tube cancers; 36 Cancer of the uterine corpus; 37 Cancer of the cervix and vagina; 38 Treating vulval cancer; 39 Gestational trophoblastic disease; Section VIII: Treating breast cancer; 40 Breast cancer; Section IX: Treating skin cancer; 41 Cutaneous melanoma; 42 Treatment of basal cell carcinoma; 43 Squamous cell carcinoma
44 Primary cutaneous T-cell lymphoma 45 Kaposi's sarcoma; Section X: Treating sarcomas; 46 Soft tissue sarcoma; Section XI: Treating central nervous system tumours; 47 Central nervous system tumours; Section XII: Treating cancers of the eye and associated structures; 48 Uveal melanoma; 49 Ocular adnexal and orbital tumours; Index
This is a book about using the best evidence to inform treatment decisions for people with cancer. It is written by oncologists for oncologists, using examples throughout to illustrate key points. The book starts off with a ""toolbox"" section, written in a way which will help those relatively new to the principles of evidence-based oncology to understand the key issues, and equip them with the basics of how to tell a good study from a bad one. The majority of the book then deals with an evidence-based summary of the common and important cancers in a structured and easy to read format around