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Regulation of transcription by anti-sigma factors / Elizabeth A. Campbell and Seth A. Darst -- Two-component signal transduction and chemotaxis / Jodi B. Lubetsky and Ann M. Stock -- Sugar recognition and bacterial attachment / Craig L. Smith [and others] -- Host receptors of bacterial origin / Calvin K. Yip [and others] -- The chaperone-usher pathway of pilus fiber biogenesis / Frederic G. Sauer, Scott J. Hultgren, and Gabriel Waksman -- Structure and assembly of type IV pilins / Katrina T. Forest -- Sortase pathways in gram-positive bacteria / Kevin M. Connolly and Robert T. Clubb -- Structural determinants of Haemophilus influenzae adherence to host epithelia: variations on type V secretion / Neeraj K. Surana [and others] -- Type III secretion machinery and effectors / C. Erec Stebbins -- Type IV secretion machinery / Gunnar Schröder, Savvas N. Savvides, Gabriel Waksman, and Erich Lanka -- Injectosomes in gram-positive bacteria / Rodney K. Tweten and Michael Caparon -- Toll/interleukin-1 receptors and innate immunity / Liang Tong.
This new text offers a comprehensive, up-to-date account of those structural classes of antibiotics that have had an impact in human infectious disease. While most of the attention is on natural products with antibiotic activity elaborated by microbes to act as chemical weapons on neighboring bacteria, synthetic chemicals with antibiotic activity are also discussed.
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