Details

Autor(en) / Beteiligte

• Diana, Patrizia,
• Cirrincione, Girolamo,

Titel

Biosynthesis of heterocycles : from isolation to gene cluster

Auflage

1st ed

Ort / Verlag

Hoboken, New Jersey : Wiley,

Erscheinungsjahr

2015

Link zum Volltext

• Wiley Online Library - AutoHoldings Books

Beschreibungen/Notizen

• "A John Wiley & Sons, Inc., publication."
• Includes bibliographical references at the end of each chapters and index.
• Cover; Contents; Preface; Acknowledgments; Chapter 1 Introduction; 1.1 Natural Products: Primary and Secondary Metabolites; 1.2 Common Reactions in Secondary Metabolites; 1.2.1 Alkylations; 1.2.2 Wagner-Meerwein Rearrangements; 1.2.3 Aldol and Claisen Reactions; 1.2.4 Schiff Base Formation and Mannich Reactions; 1.2.5 Transaminations; 1.2.6 Decarboxylations; 1.2.7 Oxidation and Reduction Reactions; 1.2.8 Dehalogenation/Halogenation Reactions; 1.2.9 Glycosylation Reactions; References; Chapter 2 Techniques for Biosynthesis; 2.1 Isotopic Labeling; 2.1.1 Stable Isotopes
• 2.1.2 Radioactive Isotopes2.2 Gene Coding for Enzymes; 2.3 Combinatorial Biosynthesis; References; Chapter 3 Three-Membered Heterocyclic Rings and Their Fused Derivatives; 3.1 Aziridines and Azirines; 3.1.1 Azicemicins; 3.1.2 Miraziridine; 3.1.3 Maduropeptin; 3.1.4 Azinomycins; 3.1.5 Ficellomycin; 3.1.6 Mitomycins; 3.1.7 Azirinomycin and Related Azirines; 3.2 Oxiranes and Oxirenes; 3.2.1 Fosfomycin; 3.2.2 AK, HC, and AF toxins; 3.2.3 Cerulenin; 3.2.4 Polyhydroxyalkanoates; 3.2.5 Epoxyrollins; 3.2.6 Asperlactone, Aspyrone, Asperline; 3.2.7 Tajixanthone; 3.2.8 Cyclomarin; 3.2.9 Cyclopenin
• 3.2.10 Ovalicin and Fumagillin3.2.11 Methylenomycin A; 3.2.12 Antibiotic LL-C10037; 3.2.13 Manumycins; 3.2.14 Scopolamine; 3.2.15 Iridoid Glucosides; 3.2.16 Cordiaquinone; 3.2.17 Cyclizidine and Indolizomycin; 3.2.18 Enediyne Antibiotics; 3.2.19 Macrolides; 3.2.20 Epothilones; 3.2.21 Pimaricin; 3.2.22 Hypothemycin; 3.2.23 Radicicol and Monocillin I; 3.2.24 Trichothecenes; 3.2.25 Sporolides A and B; References; Chapter 4 Four-Membered Heterocyclic Rings and Their Fused Derivatives; 4.1 Azetidine and Azetines; 4.1.1 Azetidine-2-carboxylic acid; 4.1.2 Polyoxins; 4.1.3 Mugineic Acids
• 4.1.4 Tabtoxin and Tabtoxinine-β-lactam4.1.5 Nocardicins; 4.1.6 Thienamycin; 4.1.7 Clavulanic Acid and Clavams; 4.1.8 Penicillins and Cephalosporins; 4.2 Oxetanes; 4.2.1 Oxetanocins; 4.2.2 Salinosporamides; 4.2.3 Taxol; 4.3 Dithiethanes; 4.3.1 Tropodithietic acid and Thiotropocin; References; Chapter 5 Five-Membered Heterocyclic Rings and Their Fused Derivatives; 5.1 Pyrroles (Including Tetrapyrroles); 5.1.1 2-Acetyl-1-pyrroline; 5.1.2 Pyrrolnitrin; 5.1.3 Broussonetines; 5.1.4 Prodigiosin and Undecylprodigiosin; 5.1.5 Anatoxin-a and Homoanatoxin-a; 5.1.6 Nostopeptolides A
• 5.1.7 Pyrrolizidine Alkaloids5.1.8 Toyocamycin and Sangivamycin; 5.1.9 Tetrapyrroles; 5.2 Indoles; 5.2.1 Indole-3-acetic acid and Glucobrassicin; 5.2.2 Camalexin; 5.2.3 Cyclomarazines; 5.2.4 Rebeccamycin and Staurosporine; 5.2.5 Paxilline; 5.3 Furans; 5.3.1 Furanomycin; 5.3.2 Xenofuranones A and B; 5.3.3 Acyl α- L-Rhamnopyranosides and Rhamnosyllactones; 5.3.4 Tuscolid and Tuscoron A and B; 5.3.5 Tetronomycin and Tetronasin; 5.3.6 Nonactin and Macrotetrolides; 5.3.7 Furanonaphthoquinone I; 5.4 Thiophenes; 5.5 Pyrazoles; 5.6 Imidazoles; 5.6.1 Histidine; 5.6.2 Amaranzole A; 5.6.3 Oroidin
• 5.6.4 Nikkomycins
• This book describes biosynthetic methods to synthesize heterocycliccompounds, offering a guide for the development of new drugs basedon natural products. The authors explain the role of naturalproducts in chemistry and their formation along with importantanalytical methods and techniques for working withheterocycles. Covers methods and techniques: isotopic labelling,enzymes and mutants, and pathway identification Provides a thorough resource of informationspecifically on heterocyclic natural products and their practicalbiosynthetic relevance Explains the role of natural products in chemistry a
• English
• Description based on print version record.