Details

Autor(en) / Beteiligte

• Osborn, Helen M. I

Titel

Carbohydrates [electronic resource]

Link zum Volltext

• Elsevier Books AutoHoldings

Beschreibungen/Notizen

• Description based upon print version of record.
• Includes bibliographical references and index.
• Front Cover; Carbohydrates; Copyright Page; Contents; Chapter 1. An Introduction to Carbohydrate Synthesis; 1.1 Biological roles of carbohydrates; 1.2 Synthesis of carbohydrates; References; Chapter 2. Selective Hydroxyl Protection and Deprotection; 2.1 Introduction; 2.2 Hydroxyl group reactivity; 2.3 Ethers; 2.4 Esters; 2.5 Carbonates; 2.6 Acetals; 2.7 Experimental procedures; References; Chapter 3. Synthesis and Activation of Carbohydrate Donors: Acetates, Halides, Phenyl selenides and Glycals; 3.1 Introduction; 3.2 Acetates; 3.3 Halides; 3.4 Phenyl selenides; 3.5 Glycals; References
• Chapter 4. Synthesis and Activation of Carbohydrate Donors: Thioglycosides and Sulfoxides4.1 Introduction; 4.2 Thioglycosides; 4.3 Sulfoxides; References; Chapter 5. Synthesis and Activation of Carbohydrate Donors: Acetimidates, n-Pentenyl and Vinyl Glycosides; 5.1 The trichloroacetimidate method; 5.2 Use of n-pentenyl glycosides as glycosyl donors; 5.3 Use of vinyl glycosides as glycosyl donors; 5.4 Overall summary; References; Chapter 6. Modern Glycosidation Methods: Tuning of Reactivity; 6.1 Introduction; 6.2 Influence of protecting groups; 6.3 Influence of leaving group; 6.4 Summary
• ReferencesChapter 7. Modern Glycosidation Methods: Orthogonal Glycosidation; 7.1 Introduction; 7.2 Orthogonal glycosidations; References; Chapter 8. The Stereoselective Synthesis of β-Mannosides; 8.1 The natural occurrence of β-mannosides; 8.2 Problems associated with β-mannoside synthesis; 8.3 Synthetic methods; 8.4 Conclusion; References; Chapter 9. Synthesis of Sialic Acid Containing Carbohydrates; 9.1 Introduction; 9.2 Sialic acid donors; 9.3 Sialylation in oligosaccharide synthesis; References; Chapter 10. The Synthesis of Glycosyl Amino Acids; 10.1 Introduction
• 10.2 O-Glycosylamino acids and O-glycopeptides10.3 N-Glycosylamino acids and N-glycopeptides; 10.4 Solid phase synthesis of N- and O-glycosylamino acids and N- and O-glycopeptides; 10.5 Conclusion; 10.6 Experimental procedures; References; Chapter 11. The Synthesis of C-linked Glycosides; 11.1 Introduction; 11.2 Synthetic methods; 11.3 Conclusion; References; Chapter 12. The Uses of Glycoprocessing Enzymes in Synthesis; 12.1 Introduction; 12.2 Glycosidases; 12.3 Glycosyltransferases; 12.4 Overall summary; References; Index
• There is a vast and often bewildering array of synthetic methods and reagents available to organic chemists today. The Best Synthetic Methods series allows the practising synthetic chemist to choose between all the alternatives and assess their real advantages and limitations. Each chapter in this book details a particular theme associated with carbohydrate synthesis. A brief review of the subject area is provided, but the emphasis in all cases is on describing efficient practical methods to effect the transformations described. In order for the roles of carbohydra
• English