Details

Autor(en) / Beteiligte

• Watson, Ronald R
• Meester, Fabien De,

Titel

Omega-3 fatty acids in brain and neurological health

Ort / Verlag

London, UK : Elsevier,

Erscheinungsjahr

[2014]

Link zum Volltext

• Elsevier Books AutoHoldings

Beschreibungen/Notizen

• Description based upon print version of record.
• Includes bibliographical references and index.
• Front Cover; Omega-3 Fatty Acids in Brain and Neurological Health; Copyright Page; Contents; Preface; List of Contributors; Acknowledgments; 1 Enhanced Longevity and Role of Omega-3 Fatty Acids; Introduction; Longevity; Food Restriction for Enhanced Longevity; Calorie Restriction for Longevity; Smoking and Reduced Longevity; Genetics, a Key Modifier of Longevity; Genetic Diseases and Longevity; Genomics; Environmental Factors and Longevity; Animal Tests and Longevity; Omega-3 Fatty Acids and Longevity; References; Further Reading
• 2 Molecular Gerontology: Principles and Perspectives for InterventionsIntroduction; Homeostasis Versus Homeodynamics; Molecular Basis of Aging; Free Radical Theory of Aging; Protein Error Theory of Aging; From FRTA and PETA to Higher Order Theories; Genetics, Post-Genetics, and Epigenetics of Aging; Epigenetics of Aging; Aging Interventions; Gene Therapy; Manipulating the Milieu; Hormetics, Hormesis, and Hormetins; References; 3 Peroxisomal Pathways, their Role in Neurodegenerative Disorders and Therapeutic Strategies; Peroxisomes; Ether Lipid Synthesis; α-oxidation; β-oxidation
• Peroxisomal PathologiesLeukodystrophies; X-linked Adrenoleukodystrophy; Lipid and Steroid Hormone Modifications; Biological Markers of X-ALD; Therapeutic Strategies; Fatty Acids and Dietary Intervention; Hormone Replacement Therapy; Gene Therapy; Demyelination and Other Leukodystrophies; Conclusion; References; 4 Unregulated Lipid Peroxidation in Neurological Dysfunction; Introduction; Lipid Oxidation Biomarkers for Neurological Dysfunction; Lipid Peroxidation Products from Linoleic Acid; Lipid Peroxidation Products from AA; Hydroxyeicosatetraenoic Acids; F2-Isoprostanes; Isofurans
• Lipid Peroxidation Products from Docosahexaenoic AcidNeuroprostanes; Neurofurans; Lipid Peroxidation-Derived Short-Chain Aldehydes; Lipid Peroxidation Products from Cholesterol; Neurological Dysfunction Associated with Lipid Peroxidation; Mechanisms of Free Radical Production in Neurological Disorders; Alzheimer's Disease; Parkinson's Disease; Amyotrophic Lateral Sclerosis; Stroke; Down Syndrome; Other Neurological Dysfunctions in Childhood; Therapeutic Intervention with Antioxidants for Neurological Dysfunction; References; Additional References
• 5 Obesity, Western Diet Intake, and Cognitive ImpairmentObesity and Cognitive Impairment; Western Diet Intake and Cognitive Impairment; Western Diet Intake and Cognitive Impairment: Underlying Neuroendocrine Mechanisms; Summary; References; 6 Genetic Risk Factors for Diabetic Neuropathy; Diabetes Mellitus and Its Complications; Diabetic Neuropathy: General Characteristics; Risk Factors for Diabetic Neuropathy and pathophysiological Mechanisms; Genetic Risk Factors for Diabetic Neuropathy; Potential Use of Genetic Risk Factors in Clinical Practice; References
• 7 n-3 Fatty Acid-Derived Lipid Mediators against Neurological Oxidative Stress and Neuroinflammation
• Research has clearly established a link between omega-3 fatty acids and general health, particularly cardiovascular health. Omega-3 Fatty Acids in Brain and Neurological Health is the first book to focus exclusively on the role of omega-3 fatty acids on general brain health. The articles in this collection illustrate omega-3 fatty acids' importance in longevity, cognitive impairment, and structure and function of the brain's neurons. Research has established links between omega-3 fatty acids and the developing brain, aging, dementia, Alzheimer's disease and multiple sclerosis.
• English
• Description based on online resource; title from PDF title page (ebrary, viewed July 7, 2014).