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Front Cover; Quantitative Functional Brain Imaging with Positron Emission Tomography; Copyright Page; Contents; Contributors; Preface; Acknowledgments; SECTION I: DATA ACQUISITION AND QUANTIFICATION; Chapter 1. Brain Imaging in Small Animals Using MicroPET; Chapter 2. Design of a High-Resolution, High-Sensitivity PET Camera for Human Brains and Small Animals; Chapter 3. The Road to Simultaneous PET/MR Images of the Brain; Chapter 4. Brain PET Studies with a High Sensitivity Fully Three-Dimensional Tomograph
Chapter 5. Emission-Transmission Realignment Using a Simultaneous Emission-Transmission Postinjection ScanChapter 6. Optimization of H2O Dose and Data Acquisition in Three-Dimensional Activation Studies Using an ECAT EXACT HR-47 PET Camera and Voxel-by-Voxel t-Statistic; Chapter 7. Parametric Image Reconstruction Using Spectral Analysis of (Rebinned) Three-Dimensional Projection Data; Chapter 8. Multislice PET Quantitation Using Three-Dimensional Volumes of Interest; Chapter 9. Absolute PET Quantification with Correction for Partial Volume Effects within Cerebral Structures
Chapter 10. Pixel- versus Region-Based Partial Volume Correction in PETChapter 11. Impact of Partial Volume Correction on Kinetic Parameters: Preliminary Experience in Patient Studies; SECTION II: IMAGE PROCESSING; Chapter 12. Performance Characterization of a Feature-Matching Axial Smoothing Method for Brain PET Images; Chapter 13. Registration of Multitracer PET Data; Chapter 14. Multimodality Brain Image Registration Using a Three-Dimensional Photogrammetrically Derived Surface; Chapter 15. Classification of Dynamic PET Images Using a Priori Kinetic Factors
Chapter 16. Methodology for Statistical Parametric Mapping of [18F]Fluorodopa Uptake Rate Using Three-Dimensional PETChapter 17. Use of Nonlinear Kernel Analysis to Evaluate ""Badness-of-Fit"" of the Transformation of PET Images into Stereotactic Space: Application to Alzheimer's Disease; Chapter 18. Data Extraction from Brain PET Images Using Three-Dimensional Stereotactic Surface Projections; Chapter 19. A Method for Surface-Based Quantification of Functional Data from the Human Cortex; SECTION III: APPLICATIONS
Chapter 20. Sequential Experimental PET: Voxel-Based Analysis Reveals Spatiotemporal Dynamics of Perfusion in Transient Focal Cerebral IschemiaChapter 21. Estimation of Ischemic Cerebral Blood Flow Using [15O]Water and PET without Arterial Blood Sampling; Chapter 22. Suitability of [15O]Water and PET to Detect Activation-Induced Cerebral Blood Flow Changes in Brain Tissue Altered by Brain Tumors; Chapter 23. Magnetic Resonance Imaging-Guided Language Activation PET in Patients: Technical Aspects and Clinical Results
Chapter 24. Brain Networks of Motor Behavior Assessed by Principal Component Analysis
This book presents the latest scientific developments in the field of positron emission tomography (PET) dealing with data acquisition, image processing, applications, statistical analysis, tracer development, parameter estimation, and kinetic modeling. It covers improved methodology and the application of existing techniques to new areas. The text also describes new approaches in scanner design and image processing, and the latest techniques for modeling and statistical analyses. This volume will be a useful reference for the active brain PET scientist, as well as a valuable introduction for