Details

Autor(en) / Beteiligte

• Poole-Warren, L.,
• Martens, P.,
• Green, R.,

Titel

Biosynthetic polymers for medical applications

Ort / Verlag

Waltham, MA : Elsevier,

Erscheinungsjahr

[2016]

Link zum Volltext

• Elsevier Books AutoHoldings

Beschreibungen/Notizen

• Description based upon print version of record.
• Includes bibliographical references and index.
• Front Cover; Related titles; Biosynthetic Polymers for Medical Applications; Copyright; Contents; List of contributors; Woodhead Publishing Series in Biomaterials; Part One - Introduction and fundamentals; 1 - Introduction to biomedical polymers and biocompatibility; 1.1 Introduction; 1.2 Natural or biological polymers; 1.2.1 Extracellular matrix; 1.2.2 Isolation and processing of natural polymers; 1.2.3 Protein polymers; 1.2.4 Carbohydrate-based polymers; 1.3 Advantages and disadvantages of natural polymers; 1.3.1 Biological polymer benefits; 1.3.2 Limitations of natural polymers
• 1.4 Biosynthetic polymers1.5 Conclusion; References; 2 - Nondegradable synthetic polymers for medical devices and implants; 2.1 Introduction; 2.1.1 Introduction to various classes of synthetic polymers; 2.2 Ultra-high molecular weight poly(ethylene) (UHMWPE); 2.2.1 Biomedical applications of UHMWPE; 2.2.2 Biocompatibility and stability of UHMWPE; 2.3 Polypropylene (PP); 2.3.1 Biomedical applications of PP; 2.4 Poly(methyl methacrylate) (PMMA); 2.4.1 Biomedical applications of PMMA; 2.4.2 Biocompatibility and stability of PMMA; 2.5 Polyurethane (PU); 2.5.1 Synthesis and properties of PU
• 2.5.2 Biostability and applications of PU2.6 Poly(dimethyl siloxane) (PDMS); 2.6.1 Chemistry and synthesis of PDMS; 2.6.2 Biomedical applications of PDMS; 2.6.3 Biocompatibility and stability of PDMS; 2.7 Polyether ether ketone (PEEK); 2.7.1 Synthesis and properties of PEEK; 2.7.2 Biocompatibility and implant applications of PEEK; 2.8 Future directions; References; 3 - Biodegradable and bioerodible polymers for medical applications; 3.1 Introduction; 3.2 Concepts and terminology; 3.2.1 Biodegradable and bioerodible; 3.2.2 Natural and synthetic polymers; 3.2.3 Controlled release
• 3.2.3.1 Temporal control3.2.3.2 Distribution control; 3.2.4 Polymer-drug conjugates; 3.2.5 Polymeric delivery systems; 3.2.5.1 Hydrogels; 3.2.5.2 Self-assembled systems; 3.2.5.3 Complexes; 3.3 Motivating factors for using polymer-drug conjugates; 3.3.1 Passive accumulation: drug targeting via the EPR effect; 3.3.2 Site-specific drug release; 3.3.3 Improved stabilisation; 3.3.4 Multivalent interactions; 3.4 Current and future trends; 3.4.1 Bioactive polymers; 3.4.2 Polymers that degrade into bioactives; Acknowledgments; References; Part Two - Coatings and surface modifications
• 4 - Bio-inspired antimicrobial polymers4.1 Introduction; 4.2 Naturally occurring AMPs; 4.3 Synthetic polymer mimics of AMPs; 4.3.1 Generation of amphiphilicity; 4.3.1.1 Single pendants: the use of monomers bearing a single hydrophobic or cationic pendant group; 4.3.1.2 Dual pendants: the use of monomers that contain both hydrophilic and cationic pendant groups connected to the same centre; 4.3.1.3 Serial pendants: the use of monomers that contain both hydrophilic and cationic groups joined in series within one monomer unit; 4.3.2 Polymerisation methods; 4.3.3 Cationic to hydrophobic balance
• 4.3.4 Source and location of charge
• Description based on print version record.