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SAR towards indoline and 3-azaindoline classes of IDO1 inhibitors

Bioorganic & medicinal chemistry letters, 2021-09, Vol.47, p.128214-128214, Article 128214

2021

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Variations in the C-unit of bedaquiline provides analogues with improved biology and pharmacology

Bioorganic & medicinal chemistry, 2020-01, Vol.28 (1), p.115213, Article 115213

2020

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Structure activity relationships of benzyl C-region analogs of 2-(3-fluoro-4-methylsulfonamidophenyl)propanamides as potent TRPV1 antagonists

Bioorganic & medicinal chemistry, 2015-11, Vol.23 (21), p.6844-6854

2015

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Design, synthesis and biological evaluation of (2S,3R,4R,5S,6R)-5-fluoro-6-(hydroxymethyl)-2-aryltetrahydro-2H-pyran-3,4-diols as potent and orally active SGLT dual inhibitors

Bioorganic & medicinal chemistry letters, 2018-11, Vol.28 (21), p.3446-3453

2018

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Synthesis, biological evaluation, and molecular docking analysis of phenstatin based indole linked chalcones as anticancer agents and tubulin polymerization inhibitors

Bioorganic chemistry, 2020-12, Vol.105, p.104447, Article 104447

2020

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N-sulfonyl peptide-hybrids as a new class of dengue virus protease inhibitors

European journal of medicinal chemistry, 2023-05, Vol.251, p.115227-115227, Article 115227

2023

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Chemical structure of hydrolysates of cereulide and their time course profile

Bioorganic & medicinal chemistry letters, 2020-05, Vol.30 (9), p.127050-127050, Article 127050

2020

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Synthesis and biological evaluation of clovamide analogues as potent anti-neuroinflammatory agents in vitro and in vivo

European journal of medicinal chemistry, 2018-05, Vol.151, p.261-271

2018

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Structure-activity relationships for unit C pyridyl analogues of the tuberculosis drug bedaquiline

Bioorganic & medicinal chemistry, 2019-04, Vol.27 (7), p.1283-1291

2019

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Structure, function and regulation of the hsp90 machinery

Biomedical journal, 2013-05, Vol.36 (3), p.106

2013

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Discovery of novel pan-genotypic HCV NS5A inhibitors containing a novel tetracyclic core

Bioorganic & medicinal chemistry letters, 2019-03, Vol.29 (5), p.700-706

2019

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Pyridine C-region analogs of 2-(3-fluoro-4-methylsulfonylaminophenyl)propanamides as potent TRPV1 antagonists

European journal of medicinal chemistry, 2015-03, Vol.93, p.101-108

2015

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Design, synthesis, and evaluation of amphiphilic sofalcone derivatives as potent Gram-positive antibacterial agents

European journal of medicinal chemistry, 2020-09, Vol.202, p.112596, Article 112596

2020

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2-(4-Methylsulfonylaminophenyl) propanamide TRPV1 antagonists: Structure–activity relationships in the B and C-regions

Bioorganic & medicinal chemistry, 2012-02, Vol.20 (3), p.1310-1318

2012

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Biarylmethoxy 2-nitroimidazooxazine antituberculosis agents: Effects of proximal ring substitution and linker reversal on metabolism and efficacy

Bioorganic & medicinal chemistry letters, 2015-09, Vol.25 (18), p.3804-3809

2015

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Nutrient‐driven O‐GlcNAc in proteostasis and neurodegeneration

Journal of neurochemistry, 2018-01, Vol.144 (1), p.7-34

2018

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Synthesis of N-benzenesulfonamide-1H-pyrazoles bearing arylsulfonyl moiety: Novel celecoxib analogs as potent anti-inflammatory agents

European journal of medicinal chemistry, 2014-06, Vol.80, p.416-422

2014

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Potential of prodendronic polyamines with modulated segmental charge density as novel coating for fast and efficient analysis of peptides and basic proteins by CE and CE-MS

Electrophoresis, 2015-07, Vol.36 (14), p.1564-1571

2015

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Fluoromethylcyclopropylamine derivatives as potential in vivo toxicophores – A cautionary disclosure

Bioorganic & medicinal chemistry letters, 2019-02, Vol.29 (4), p.560-562

2019

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Discovery of IDO1 inhibitors containing a decahydroquinoline, decahydro-1,6-naphthyridine, or octahydro-1H-pyrrolo[3,2-c]pyridine scaffold

Bioorganic & medicinal chemistry letters, 2021-10, Vol.49, p.128314-128314, Article 128314

2021

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Kappa opioids and the modulation of pain

Psychopharmacology, 2010-06, Vol.210 (2), p.109-119

2010

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Modifications in the Head Group and in the Spacer of Cholesterol-based Cationic Lipids Promote Transfection in Melanoma B16-F10 Cells and Tumours

Journal of drug targeting, 2004-01, Vol.12 (1), p.25-38

2004

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Targeting the transmembrane domain 5 of latent membrane protein 1 using small molecule modulators

European journal of medicinal chemistry, 2021-03, Vol.214, p.113210, Article 113210

2021

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On the significance of an alternate pathway of melatonin synthesis via 5-methoxytryptamine: comparisons across species

Journal of pineal research, 2016-08, Vol.61 (1), p.27-40

2016

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NAA10 controls osteoblast differentiation and bone formation as a feedback regulator of Runx2

Nature communications, 2014-11, Vol.5 (1), p.5176-5176, Article 5176

2014

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SAR towards indoline and 3-azaindoline classes of IDO1 inhibitors

Variations in the C-unit of bedaquiline provides analogues with improved biology and pharmacology

Structure activity relationships of benzyl C-region analogs of 2-(3-fluoro-4-methylsulfonamidophenyl)propanamides as potent TRPV1 antagonists

Design, synthesis and biological evaluation of (2S,3R,4R,5S,6R)-5-fluoro-6-(hydroxymethyl)-2-aryltetrahydro-2H-pyran-3,4-diols as potent and orally active SGLT dual inhibitors

Synthesis, biological evaluation, and molecular docking analysis of phenstatin based indole linked chalcones as anticancer agents and tubulin polymerization inhibitors

N-sulfonyl peptide-hybrids as a new class of dengue virus protease inhibitors

Chemical structure of hydrolysates of cereulide and their time course profile

Synthesis and biological evaluation of clovamide analogues as potent anti-neuroinflammatory agents in vitro and in vivo

Structure-activity relationships for unit C pyridyl analogues of the tuberculosis drug bedaquiline

Structure, function and regulation of the hsp90 machinery

Discovery of novel pan-genotypic HCV NS5A inhibitors containing a novel tetracyclic core

Pyridine C-region analogs of 2-(3-fluoro-4-methylsulfonylaminophenyl)propanamides as potent TRPV1 antagonists

Design, synthesis, and evaluation of amphiphilic sofalcone derivatives as potent Gram-positive antibacterial agents

2-(4-Methylsulfonylaminophenyl) propanamide TRPV1 antagonists: Structure–activity relationships in the B and C-regions

Biarylmethoxy 2-nitroimidazooxazine antituberculosis agents: Effects of proximal ring substitution and linker reversal on metabolism and efficacy

Nutrient‐driven O‐GlcNAc in proteostasis and neurodegeneration

Synthesis of N-benzenesulfonamide-1H-pyrazoles bearing arylsulfonyl moiety: Novel celecoxib analogs as potent anti-inflammatory agents

Potential of prodendronic polyamines with modulated segmental charge density as novel coating for fast and efficient analysis of peptides and basic proteins by CE and CE-MS

Fluoromethylcyclopropylamine derivatives as potential in vivo toxicophores – A cautionary disclosure

Discovery of IDO1 inhibitors containing a decahydroquinoline, decahydro-1,6-naphthyridine, or octahydro-1H-pyrrolo[3,2-c]pyridine scaffold

Kappa opioids and the modulation of pain

Modifications in the Head Group and in the Spacer of Cholesterol-based Cationic Lipids Promote Transfection in Melanoma B16-F10 Cells and Tumours

Targeting the transmembrane domain 5 of latent membrane protein 1 using small molecule modulators

On the significance of an alternate pathway of melatonin synthesis via 5-methoxytryptamine: comparisons across species

NAA10 controls osteoblast differentiation and bone formation as a feedback regulator of Runx2

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