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Activation and Inhibition of Sodium-Hydrogen Exchanger Is a Mechanism That Links the Pathophysiology and Treatment of Diabetes Mellitus With That of Heart Failure

Circulation (New York, N.Y.), 2017-10, Vol.136 (16), p.1548-1559

Packer, Milton

2017

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Antihypertensive and Renal Mechanisms of SGLT2 (Sodium-Glucose Linked Transporter 2) Inhibitors

Hypertension (Dallas, Tex. 1979), 2020-04, Vol.75 (4), p.894-901

Wilcox, Christopher S

2020

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Proton channels and exchangers in cancer

Biochimica et biophysica acta, 2015-10, Vol.1848 (10), p.2715-2726

2015

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Na+/H+ antiporter (NHE1) and lactate/H+ symporters (MCTs) in pH homeostasis and cancer metabolism

Biochimica et biophysica acta, 2016-10, Vol.1863 (10), p.2465-2480

2016

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Physiology, pharmacology and pathophysiology of the pH regulatory transport proteins NHE1 and NBCn1: similarities, differences, and implications for cancer therapy

Current pharmaceutical design, 2012-04, Vol.18 (10), p.1345

2012

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Gastrointestinal Inhibition of Sodium-Hydrogen Exchanger 3 Reduces Phosphorus Absorption and Protects against Vascular Calcification in CKD

Journal of the American Society of Nephrology, 2015-05, Vol.26 (5), p.1138-1149

2015

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Amiloride inhibits macropinocytosis by lowering submembranous pH and preventing Rac1 and Cdc42 signaling

The Journal of cell biology, 2010-02, Vol.188 (4), p.547-563

2010

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Tenapanor Treatment of Patients With Constipation-Predominant Irritable Bowel Syndrome: A Phase 2, Randomized, Placebo-Controlled Efficacy and Safety Trial

The American journal of gastroenterology, 2017-05, Vol.112 (5), p.763-774

2017

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Emerging roles of Na⁺/H⁺ exchangers in epilepsy and developmental brain disorders

Progress in neurobiology, 2016-03, Vol.138-140, p.19-35

2016

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NHE-1: Still a viable therapeutic target

Journal of molecular and cellular cardiology, 2013-08, Vol.61, p.77-82

Karmazyn, Morris

2013

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Cortisol regulates Na+ uptake in zebrafish, Danio rerio, larvae via the glucocorticoid receptor

Molecular and cellular endocrinology, 2012-11, Vol.364 (1-2), p.113-125

2012

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Ammonia excretion via Rhcg1 facilitates Na⁺ uptake in larval zebrafish, Danio rerio, in acidic water

American journal of physiology. Regulatory, integrative and comparative physiology, 2011-11, Vol.301 (5), p.R1517-R1528

2011

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Effects of Inhibitors of SLC9A-Type Sodium-Proton Exchangers on Survival Motor Neuron 2 ( SMN2 ) mRNA Splicing and Expression

Molecular pharmacology, 2022-08, Vol.102 (2), p.92-105

2022

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SGLT2 inhibition and COVID‐19: The road not taken

European journal of clinical investigation, 2020-12, Vol.50 (12), p.e13339-n/a

2020

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pH sensing by FAK-His58 regulates focal adhesion remodeling

The Journal of cell biology, 2013-09, Vol.202 (6), p.849-859

2013

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Disruption of Na+,HCO3― Cotransporter NBCn1 (slc4a7) Inhibits NO-Mediated Vasorelaxation, Smooth Muscle Ca2+ Sensitivity, and Hypertension Development in Mice

Circulation (New York, N.Y.), 2011-10, Vol.124 (17), p.1819-1829

2011

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Osmotic Regulation Is Required for Cancer Cell Survival under Solid Stress

Biophysical journal, 2015-10, Vol.109 (7), p.1334-1337

2015

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KR-33028, a potent inhibitor of the Na+/H+ exchanger NHE1, suppresses metastatic potential of triple-negative breast cancer cells

Biochemical pharmacology, 2016-10, Vol.118, p.31-39

2016

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Cariporide and other new and powerful NHE1 inhibitors as potentially selective anticancer drugs--an integral molecular/biochemical/metabolic/clinical approach after one hundred years of cancer research

Journal of translational medicine, 2013-11, Vol.11 (1), p.282-282

2013

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Specificity of NHERF1 regulation of GPCR signaling and function in human airway smooth muscle

The FASEB journal, 2019-08, Vol.33 (8), p.9008-9016

2019

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Na+-H+ exchanger, pH regulation and cancer

Recent patents on anti-cancer drug discovery, 2013-01, Vol.8 (1), p.85

2013

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Deciphering ion transporters, kinases and PDZ-adaptor molecules that mediate guanylate cyclase C agonist-dependent intestinal fluid loss in vivo

Biochemical pharmacology, 2020-08, Vol.178, p.114040, Article 114040

2020

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The Na⁺/H⁺ exchanger (NHE1) as a novel co-adjuvant target in paclitaxel therapy of triple-negative breast cancer cells

Oncotarget, 2015-01, Vol.6 (2), p.1262-1275

2015

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New generation ENaC inhibitors detach cystic fibrosis airway mucus bundles via sodium/hydrogen exchanger inhibition

European journal of pharmacology, 2021-08, Vol.904, p.174123-174123, Article 174123

2021

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Activation and Inhibition of Sodium-Hydrogen Exchanger Is a Mechanism That Links the Pathophysiology and Treatment of Diabetes Mellitus With That of Heart Failure

Antihypertensive and Renal Mechanisms of SGLT2 (Sodium-Glucose Linked Transporter 2) Inhibitors

Proton channels and exchangers in cancer

Na+/H+ antiporter (NHE1) and lactate/H+ symporters (MCTs) in pH homeostasis and cancer metabolism

Physiology, pharmacology and pathophysiology of the pH regulatory transport proteins NHE1 and NBCn1: similarities, differences, and implications for cancer therapy

Gastrointestinal Inhibition of Sodium-Hydrogen Exchanger 3 Reduces Phosphorus Absorption and Protects against Vascular Calcification in CKD

Amiloride inhibits macropinocytosis by lowering submembranous pH and preventing Rac1 and Cdc42 signaling

Tenapanor Treatment of Patients With Constipation-Predominant Irritable Bowel Syndrome: A Phase 2, Randomized, Placebo-Controlled Efficacy and Safety Trial

Emerging roles of Na⁺/H⁺ exchangers in epilepsy and developmental brain disorders

NHE-1: Still a viable therapeutic target

Cortisol regulates Na+ uptake in zebrafish, Danio rerio, larvae via the glucocorticoid receptor

β-catenin knockdown promotes NHERF1-mediated survival of colorectal cancer cells: implications for a double-targeted therapy

Ammonia excretion via Rhcg1 facilitates Na⁺ uptake in larval zebrafish, Danio rerio, in acidic water

Effects of Inhibitors of SLC9A-Type Sodium-Proton Exchangers on Survival Motor Neuron 2 ( SMN2 ) mRNA Splicing and Expression

SGLT2 inhibition and COVID‐19: The road not taken

pH sensing by FAK-His58 regulates focal adhesion remodeling

Disruption of Na+,HCO3― Cotransporter NBCn1 (slc4a7) Inhibits NO-Mediated Vasorelaxation, Smooth Muscle Ca2+ Sensitivity, and Hypertension Development in Mice

Osmotic Regulation Is Required for Cancer Cell Survival under Solid Stress

KR-33028, a potent inhibitor of the Na+/H+ exchanger NHE1, suppresses metastatic potential of triple-negative breast cancer cells

Cariporide and other new and powerful NHE1 inhibitors as potentially selective anticancer drugs--an integral molecular/biochemical/metabolic/clinical approach after one hundred years of cancer research

Specificity of NHERF1 regulation of GPCR signaling and function in human airway smooth muscle

Na+-H+ exchanger, pH regulation and cancer

Deciphering ion transporters, kinases and PDZ-adaptor molecules that mediate guanylate cyclase C agonist-dependent intestinal fluid loss in vivo

The Na⁺/H⁺ exchanger (NHE1) as a novel co-adjuvant target in paclitaxel therapy of triple-negative breast cancer cells

New generation ENaC inhibitors detach cystic fibrosis airway mucus bundles via sodium/hydrogen exchanger inhibition

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