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Gastrointestinal Inhibition of Sodium-Hydrogen Exchanger 3 Reduces Phosphorus Absorption and Protects against Vascular Calcification in CKD

Journal of the American Society of Nephrology, 2015-05, Vol.26 (5), p.1138-1149

2015

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Amiloride inhibits macropinocytosis by lowering submembranous pH and preventing Rac1 and Cdc42 signaling

The Journal of cell biology, 2010-02, Vol.188 (4), p.547-563

2010

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Intestinal inhibition of the Na+/H+ exchanger 3 prevents cardiorenal damage in rats and inhibits Na+ uptake in humans

Science translational medicine, 2014-03, Vol.6 (227), p.227ra36

2014

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Solute transport and oxygen consumption along the nephrons: effects of Na+ transport inhibitors

American journal of physiology. Renal physiology, 2016-12, Vol.311 (6), p.F1217-F1229

2016

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Ammonia excretion via Rhcg1 facilitates Na⁺ uptake in larval zebrafish, Danio rerio, in acidic water

American journal of physiology. Regulatory, integrative and comparative physiology, 2011-11, Vol.301 (5), p.R1517-R1528

2011

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Effects of Inhibitors of SLC9A-Type Sodium-Proton Exchangers on Survival Motor Neuron 2 ( SMN2 ) mRNA Splicing and Expression

Molecular pharmacology, 2022-08, Vol.102 (2), p.92-105

2022

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SGLT2 inhibition and COVID‐19: The road not taken

European journal of clinical investigation, 2020-12, Vol.50 (12), p.e13339-n/a

2020

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pH sensing by FAK-His58 regulates focal adhesion remodeling

The Journal of cell biology, 2013-09, Vol.202 (6), p.849-859

2013

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Specificity of NHERF1 regulation of GPCR signaling and function in human airway smooth muscle

The FASEB journal, 2019-08, Vol.33 (8), p.9008-9016

2019

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The Na⁺/H⁺ exchanger (NHE1) as a novel co-adjuvant target in paclitaxel therapy of triple-negative breast cancer cells

Oncotarget, 2015-01, Vol.6 (2), p.1262-1275

2015

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NHE8 attenuates Ca 2+ influx into NRK cells and the proximal tubule epithelium

American journal of physiology. Renal physiology, 2019-08, Vol.317 (2), p.F240-F253

2019

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MicroRNA‐19a attenuates hypoxia‐induced cardiomyocyte apoptosis by downregulating NHE‐1 expression and decreasing calcium overload

Journal of cellular biochemistry, 2020-02, Vol.121 (2), p.1747-1758

2020

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The Na+/H+-exchanger (NHE1) generates pH nanodomains at focal adhesions

Journal of cellular physiology, 2013-06, Vol.228 (6), p.1351-1358

2013

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Flupirtine enhances NHE-3-mediated Na + absorption in rat colon via an ENS-dependent mechanism

American journal of physiology: Gastrointestinal and liver physiology, 2021-08, Vol.321 (2), p.G185-G199

2021

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DJ‐1/Park7 Sensitive Na+/H+ Exchanger 1 (NHE1) in CD4+ T Cells

Journal of cellular physiology, 2017-11, Vol.232 (11), p.3050-3059

2017

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Mechanisms of pH-gradient driven transport mediated by organic anion polypeptide transporters

American Journal of Physiology: Cell Physiology, 2009-03, Vol.296 (3), p.C570-C582

2009

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Reversal of ApoE4-induced recycling block as a novel prevention approach for Alzheimer's disease

eLife, 2018-10, Vol.7

2018

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CD44 Interaction with Na+-H+ Exchanger (NHE1) Creates Acidic Microenvironments Leading to Hyaluronidase-2 and Cathepsin B Activation and Breast Tumor Cell Invasion

The Journal of biological chemistry, 2004-06, Vol.279 (26), p.26991-27007

2004

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Cisplatin-induced apoptosis involves membrane fluidification via inhibition of NHE1 in human colon cancer cells

Cancer research (Chicago, Ill.), 2007-08, Vol.67 (16), p.7865-7874

2007

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Furosemide-induced urinary acidification is caused by pronounced H+ secretion in the thick ascending limb

American journal of physiology. Renal physiology, 2015-07, Vol.309 (2), p.F146-F153

2015

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Discovery and Optimization of 1‑Phenoxy-2-aminoindanes as Potent, Selective, and Orally Bioavailable Inhibitors of the Na+/H+ Exchanger Type 3 (NHE3)

Journal of medicinal chemistry, 2016-10, Vol.59 (19), p.8812-8829

2016

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Proximal tubular NHEs: sodium, protons and calcium?

American journal of physiology. Renal physiology, 2013-08, Vol.305 (3), p.F229-F236

2013

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Role of sodium/hydrogen exchanger isoform 1 in microglial activation and proinflammatory responses in ischemic brains

Journal of neurochemistry, 2011-10, Vol.119 (1), p.124-135

2011

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The changing face of the Na+/H+ exchanger, NHE1: structure, regulation, and cellular actions

Annual review of pharmacology and toxicology, 2002-01, Vol.42 (1), p.527-552

2002

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Gastrointestinal Inhibition of Sodium-Hydrogen Exchanger 3 Reduces Phosphorus Absorption and Protects against Vascular Calcification in CKD

Amiloride inhibits macropinocytosis by lowering submembranous pH and preventing Rac1 and Cdc42 signaling

Intestinal inhibition of the Na+/H+ exchanger 3 prevents cardiorenal damage in rats and inhibits Na+ uptake in humans

Solute transport and oxygen consumption along the nephrons: effects of Na+ transport inhibitors

β-catenin knockdown promotes NHERF1-mediated survival of colorectal cancer cells: implications for a double-targeted therapy

Ammonia excretion via Rhcg1 facilitates Na⁺ uptake in larval zebrafish, Danio rerio, in acidic water

Effects of Inhibitors of SLC9A-Type Sodium-Proton Exchangers on Survival Motor Neuron 2 ( SMN2 ) mRNA Splicing and Expression

SGLT2 inhibition and COVID‐19: The road not taken

pH sensing by FAK-His58 regulates focal adhesion remodeling

Specificity of NHERF1 regulation of GPCR signaling and function in human airway smooth muscle

The Na⁺/H⁺ exchanger (NHE1) as a novel co-adjuvant target in paclitaxel therapy of triple-negative breast cancer cells

NHE8 attenuates Ca 2+ influx into NRK cells and the proximal tubule epithelium

MicroRNA‐19a attenuates hypoxia‐induced cardiomyocyte apoptosis by downregulating NHE‐1 expression and decreasing calcium overload

The Na+/H+-exchanger (NHE1) generates pH nanodomains at focal adhesions

Flupirtine enhances NHE-3-mediated Na + absorption in rat colon via an ENS-dependent mechanism

DJ‐1/Park7 Sensitive Na+/H+ Exchanger 1 (NHE1) in CD4+ T Cells

Mechanisms of pH-gradient driven transport mediated by organic anion polypeptide transporters

Reversal of ApoE4-induced recycling block as a novel prevention approach for Alzheimer's disease

CD44 Interaction with Na+-H+ Exchanger (NHE1) Creates Acidic Microenvironments Leading to Hyaluronidase-2 and Cathepsin B Activation and Breast Tumor Cell Invasion

Cisplatin-induced apoptosis involves membrane fluidification via inhibition of NHE1 in human colon cancer cells

Furosemide-induced urinary acidification is caused by pronounced H+ secretion in the thick ascending limb

Discovery and Optimization of 1‑Phenoxy-2-aminoindanes as Potent, Selective, and Orally Bioavailable Inhibitors of the Na+/H+ Exchanger Type 3 (NHE3)

Proximal tubular NHEs: sodium, protons and calcium?

Role of sodium/hydrogen exchanger isoform 1 in microglial activation and proinflammatory responses in ischemic brains

The changing face of the Na+/H+ exchanger, NHE1: structure, regulation, and cellular actions

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