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PI3K/Akt and HIF‑1 signaling pathway in hypoxia‑ischemia (Review)

Molecular medicine reports, 2018-10, Vol.18 (4), p.3547-3554

2018

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PI3K/Akt signaling transduction pathway, erythropoiesis and glycolysis in hypoxia (Review)

Molecular medicine reports, 2019-02, Vol.19 (2), p.783-791

2019

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Leonurine protects cardiac function following acute myocardial infarction through anti‑apoptosis by the PI3K/AKT/GSK3β signaling pathway

Molecular medicine reports, 2018-08, Vol.18 (2), p.1582-1590

2018

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Metformin induces apoptosis and inhibits migration by activating the AMPK/p53 axis and suppressing PI3K/AKT signaling in human cervical cancer cells

Molecular medicine reports, 2021-01, Vol.23 (1), Article 88

2021

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Curcumin inhibits high glucose‑induced inflammatory injury in human retinal pigment epithelial cells through the ROS‑PI3K/AKT/mTOR signaling pathway

Molecular medicine reports, 2019-02, Vol.19 (2), p.1024-1031

2019

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Plant flavonoid taxifolin inhibits the growth, migration and invasion of human osteosarcoma cells

Molecular medicine reports, 2018-02, Vol.17 (2), p.3239-3245

2018

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Apigenin suppresses the apoptosis of H9C2 rat cardiomyocytes subjected to myocardial ischemia‑reperfusion injury via upregulation of the PI3K/Akt pathway

Molecular medicine reports, 2018-08, Vol.18 (2), p.1560-1570

2018

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Resveratrol inhibits the invasion and metastasis of colon cancer through reversal of epithelial‑ mesenchymal transition via the AKT/GSK‑3β/Snail signaling pathway

Molecular medicine reports, 2019-09, Vol.20 (3), p.2783-2795

2019

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Leptin receptor mediates the proliferation and glucose metabolism of pancreatic cancer cells via AKT pathway activation

Molecular medicine reports, 2020-02, Vol.21 (2), p.945-952

2020

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Apigenin induces apoptosis by regulating Akt and MAPK pathways in human melanoma cell A375SM

Molecular medicine reports, 2020-12, Vol.22 (6), p.4877-4889

2020

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LncRNA SNHG6 inhibits cell proliferation and metastasis by targeting ETS1 via the PI3K/AKT/mTOR pathway in colorectal cancer

Molecular medicine reports, 2019-09, Vol.20 (3), p.2541-2548

2019

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PI3K/Akt signaling is involved in the pathogenesis of bleomycin-induced pulmonary fibrosis via regulation of epithelial-mesenchymal transition

Molecular medicine reports, 2016-12, Vol.14 (6), p.5699-5706

2016

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miR‑320‑3p is involved in morphine pre‑conditioning to protect rat cardiomyocytes from ischemia/reperfusion injury through targeting Akt3

Molecular medicine reports, 2020-08, Vol.22 (2), p.1480-1488

2020

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Vildagliptin prevents cognitive deficits and neuronal apoptosis in a rat model of Alzheimer's disease

Molecular medicine reports, 2018-03, Vol.17 (3), p.4113-4119

2018

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Paeoniflorin inhibits IL-1β-induced chondrocyte apoptosis by regulating the Bax/Bcl-2/caspase-3 signaling pathway

Molecular medicine reports, 2018-04, Vol.17 (4), p.6194-6200

2018

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MicroRNA‑223‑induced inhibition of the FBXW7 gene affects the proliferation and apoptosis of colorectal cancer cells via the Notch and Akt/mTOR pathways

Molecular medicine reports, 2021-02, Vol.23 (2), Article 154

2021

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AIM2 inhibits the proliferation, invasion and migration, and promotes the apoptosis of osteosarcoma cells by inactivating the PI3K/AKT/mTOR signaling pathway

Molecular medicine reports, 2022-02, Vol.25 (2), Article 53

2022

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Baicalin alleviates bleomycin‑induced pulmonary fibrosis and fibroblast proliferation in rats via the PI3K/AKT signaling pathway

Molecular medicine reports, 2020-06, Vol.21 (6), p.2321-2334

2020

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Panax Notoginseng Saponins attenuates sevoflurane-induced nerve cell injury by modulating AKT signaling pathway

Molecular medicine reports, 2017-11, Vol.16 (5), p.7829-7834

2017

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8-bromo-7-methoxychrysin induces apoptosis by regulating Akt/FOXO3a pathway in cisplatin-sensitive and resistant ovarian cancer cells

Molecular medicine reports, 2015-10, Vol.12 (4), p.5100-5108

2015

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LncRNA LINC00961 regulates endothelial‑mesenchymal transition via the PTEN‑PI3K‑AKT pathway

Molecular medicine reports, 2022-07, Vol.26 (1), Article 246

2022

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Gallium ions promote osteoinduction of human and mouse osteoblasts via the TRPM7/Akt signaling pathway

Molecular medicine reports, 2020-10, Vol.22 (4), p.2741-2752

2020

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MicroRNA-28 promotes cell proliferation and invasion in gastric cancer via the PTEN/PI3K/AKT signalling pathway

Molecular medicine reports, 2018-03, Vol.17 (3), p.4003-4010

2018

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Magnesium sulfate ameliorates carbon monoxide‑induced cerebral injury in male rats

Molecular medicine reports, 2019-02, Vol.19 (2), p.1032-1039

2019

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Critical implication of the PTEN/PI3K/AKT pathway during BMP2-induced heterotopic ossification

Molecular medicine reports, 2021-04, Vol.23 (4), Article 254

2021

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PI3K/Akt and HIF‑1 signaling pathway in hypoxia‑ischemia (Review)

PI3K/Akt signaling transduction pathway, erythropoiesis and glycolysis in hypoxia (Review)

Leonurine protects cardiac function following acute myocardial infarction through anti‑apoptosis by the PI3K/AKT/GSK3β signaling pathway

Metformin induces apoptosis and inhibits migration by activating the AMPK/p53 axis and suppressing PI3K/AKT signaling in human cervical cancer cells

Curcumin inhibits high glucose‑induced inflammatory injury in human retinal pigment epithelial cells through the ROS‑PI3K/AKT/mTOR signaling pathway

Plant flavonoid taxifolin inhibits the growth, migration and invasion of human osteosarcoma cells

Apigenin suppresses the apoptosis of H9C2 rat cardiomyocytes subjected to myocardial ischemia‑reperfusion injury via upregulation of the PI3K/Akt pathway

Resveratrol inhibits the invasion and metastasis of colon cancer through reversal of epithelial‑ mesenchymal transition via the AKT/GSK‑3β/Snail signaling pathway

Leptin receptor mediates the proliferation and glucose metabolism of pancreatic cancer cells via AKT pathway activation

Apigenin induces apoptosis by regulating Akt and MAPK pathways in human melanoma cell A375SM

LncRNA SNHG6 inhibits cell proliferation and metastasis by targeting ETS1 via the PI3K/AKT/mTOR pathway in colorectal cancer

PI3K/Akt signaling is involved in the pathogenesis of bleomycin-induced pulmonary fibrosis via regulation of epithelial-mesenchymal transition

miR‑320‑3p is involved in morphine pre‑conditioning to protect rat cardiomyocytes from ischemia/reperfusion injury through targeting Akt3

Vildagliptin prevents cognitive deficits and neuronal apoptosis in a rat model of Alzheimer's disease

Paeoniflorin inhibits IL-1β-induced chondrocyte apoptosis by regulating the Bax/Bcl-2/caspase-3 signaling pathway

MicroRNA‑223‑induced inhibition of the FBXW7 gene affects the proliferation and apoptosis of colorectal cancer cells via the Notch and Akt/mTOR pathways

AIM2 inhibits the proliferation, invasion and migration, and promotes the apoptosis of osteosarcoma cells by inactivating the PI3K/AKT/mTOR signaling pathway

Baicalin alleviates bleomycin‑induced pulmonary fibrosis and fibroblast proliferation in rats via the PI3K/AKT signaling pathway

Panax Notoginseng Saponins attenuates sevoflurane-induced nerve cell injury by modulating AKT signaling pathway

8-bromo-7-methoxychrysin induces apoptosis by regulating Akt/FOXO3a pathway in cisplatin-sensitive and resistant ovarian cancer cells

LncRNA LINC00961 regulates endothelial‑mesenchymal transition via the PTEN‑PI3K‑AKT pathway

Gallium ions promote osteoinduction of human and mouse osteoblasts via the TRPM7/Akt signaling pathway

MicroRNA-28 promotes cell proliferation and invasion in gastric cancer via the PTEN/PI3K/AKT signalling pathway

Magnesium sulfate ameliorates carbon monoxide‑induced cerebral injury in male rats

Critical implication of the PTEN/PI3K/AKT pathway during BMP2-induced heterotopic ossification

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